Diet Alters Period Pain and Duration
More validation is emerging for the furin protease (“furin”) hypothesis I posited in this blog: The Furin Protease Connection: From SARS CoV-2 and Anthrax, to Diabetes and Hypertension and that is now available as a pre-print publication here.
Considering furin protease inhibitors
Scientists are validating furin inhibition as a possible pathway to addressing COVID. And in this Medical News Today article they also used anthrax as a model to study for interventions. However, the non-specific nature of medical protease inhibitors carries a very high side effect profile. Many individuals won’t be able to tolerate this intervention.
In my mind, this elevates the potential importance of luteolin, given the high in vitro furin inhibition it has demonstrated, and the animal research on its inhibition of dengue fever replication via the same mechanism.
Lifestyle factors that lower furin
We also know that 94 percent of SARS CoV-2 cases are in individuals with pre-existing conditions. We also know that the highest-associated conditions are also associated with elevated levels of baseline furin. And that furin is an important independent risk factor that trends high very early on in the journey towards cardiometabolic disease.
What is steadfastly being missed in all the papers I am reading is the urgent need for interventions to LOWER circulating furin. This risk profile (obesity, high blood glucose, high insulin, and/or high blood pressure) is highly modifiable through correcting underlying diet, environment and lifestyle habits.
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