Why Bone Loss Accelerates With Aging: The Gut–Bone Connection
I just had a really fascinating conversation with the scientists at Sōlaria biō—Mark Charbonneau and Alicia Ballok—about a line of research that genuinely made me stop and rethink how we approach bone health. We talked about their journey from isolating microbes living inside edible plants, to identifying synergistic microbial interactions, to building out the preclinical work and then taking it all the way into human clinical research. It’s a rare and thoughtful progression, and the science is compelling. Their first clinical focus has been bone loss, and the results they’ve seen so far are striking. In an early clinical study, they reported a substantial reduction in bone loss—up to 80% in certain groups—along with meaningful reductions in CTX, one of the key markers we use to assess bone turnover. They’re now recruiting for a follow-up study in postmenopausal women in collaboration with Harvard, and we’ll share details in the show notes for anyone who may be eligible. This is a rich, science-forward conversation, and I think you’ll find it as interesting as I did. ~DrKF
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