In today’s podcast, I’m talking with long time integrative medical clinician and anti-aging expert Lynne Mielke, MD about her approach to bioidentical hormones and why the Precision Analytical DUTCH is her go-to test for assessing biHRT response.
This episode is a little different from what we usually cover on New Frontiers, but it’s one I couldn’t wait to bring to you. I’ve been thinking a lot about how we—as clinicians—are supposed to keep up in this era of high-throughput technology. We’re swimming in data: labs, multi-omics, diet logs… and an ever-growing stream from wearables. There’s just so much coming at us, and too often, we’re awash in a sea of information without adequate interpretive power.
I’ve been looking forward to sharing this conversation with you because it’s one I’m truly passionate about. Today, we’re diving into the DunedinPACE epigenetic clock with one of its creators, the brilliant Dan Belsky. It’s a tool I use regularly with my patients, and one that’s transforming how we approach aging and interventions. While this show is a bit more technical than usual, the science is fascinating, and the real-world applications are incredibly valuable. This isn’t just about theory—it’s about practical insights that can change how we measure aging and track the effectiveness of the treatments we offer. Stick with us, and you’ll walk away with actionable knowledge that can make a difference in your practice. ~DrKF
When I was a kid at lunch, while my friends were eating those heavenly-looking ultraprocessed Twinkies and Ringdings and making dough balls with their white bread, I ate home-made yogurt or nutbutter sandwiches on a very dense, whole grain bread; or perhaps noshed on some sardines. Make no mistake, I went through a very rebellious phase involving Oreo cookies when I finally called the food shots in my life. But thankfully, I had gleaned enough from my mom that this phase didn’t last long. Indeed, I developed a deep appreciation for how savvy she was (and still is!) when it comes to keeping food clean, healthy and almost completely free of ultraprocessing and toxic food chemicals. She taught me the importance of avoiding ultra-processed foods and toxic food chemicals, long before it became a public health headline.
Estrogen is a life-giving hormone with which modern humans have a complicated relationship. Over two decades ago, The Women’s Health Initiative (WHI) findings mistakenly reported that combined estrogen and progestin hormone therapy increased the risk of breast cancer, coronary heart disease, stroke, and venous thromboembolism in postmenopausal women. This led to a pervasive vilification of estrogen therapy that has affected generations of women.
We’ve all had patients struggling with chronic conditions like long COVID, fibromyalgia, Lyme disease, and chronic fatigue. Despite all the tools in our functional medicine toolkit, there’s still something missing. How can we truly help them? I’m excited to have Ashok Gupta is back on the New Frontiers podcast to offer a new take on that healing from chronic illnessquestion. He explains that how many chronic diseases stem from a malfunction in the brain’s threat detection system, where the body overreacts to perceived threats, triggering immune, nervous system, or mood responses, . This creatinges a vicious cycle. Ashok shares how retraining the brain and calming the nervous system can reset the body’s response to chronic stress and presents the growing body of research supporting thehis Gupta Program, including new subjective measurements like CRP showing its impact. What excites me most is the potential for this approach to help some of my toughest-to-treat patients. With more studies emerging, I’m increasingly hopeful this could be a game-changer. It’s a conversation you won’t want to miss! ~DrKF
Discover the truth about olive oil. Dr. Artemis Morris busts common myths and shares science-backed benefits of this Mediterranean staple.
Join me for a fascinating conversation around an exciting breakthrough in dementia detection that’s offering real hope for early intervention. Dr. Hans Frykman, Chief Scientific Officer at Neurocode Laboratories, is here to share groundbreaking insights into cutting-edge biomarkers that can identify Alzheimer’s disease before symptoms even appear. What’s even more fascinating is how these same tools are revealing neuroinflammation caused by infections, including COVID, Lyme disease, and mold exposure—issues that are incredibly relevant in functional medicine today. The assays Dr. Frykman and his team have developed are transforming the way we think about diagnosing and addressing neurodegeneration. We’re talking about a potential game-changer that allows us to intervene earlier, reverse damage, and ultimately improve the trajectory of these conditions. This is an extraordinary time in science and medicine, and the work we’re discussing today is at the forefront of it all. Don’t miss out on how this could reshape your practice. ~DrKF
In this episode, we’re diving into exposomics—one of the most cutting-edge fields in environmental medicine. We in the functional medicine space have long embraced this approach that focuses on the lifelong effects of environmental exposures, from the prenatal period on, and how these exposures shape our health over time. I’m thrilled to have Drs. Robert and Rosalind Wright with us, pioneers in this field at Mount Sinai to share their research exploring how environmental factors, from lead and air pollution to social stress, can influence chronic diseases like asthma, obesity, Alzheimer’s, and autism.
Join me and Dr. Colleen Cutcliffe, my brilliant friend, scientist, and the powerhouse CEO of Pendulum, for our deepest dive yet into all things Akkermansia. This free-flowing conversation will take your understanding of this extraordinary strain to a whole new level. We’ll explore Akkermansia’s pivotal role in metabolic health—think cravings, weight regulation, A1C—and why we’re deficient in the first place. Plus, we’ll discuss its connection to stress, anxiety, and even neurodegenerative diseases. We’ll also dive into the hotly debated topic of Akkermansia’s impact on MS, unpacking both sides of the controversy. And, we’ll touch on its promising influence on hormonal balance, from infertility to menopause. As someone who’s deeply invested in science, I’m personally bullish on Akkermansia and trust Pendulum’s products as part of my own foundational health stack. With groundbreaking science and fresh insights, this episode will change the way you approach your practice. ~DrKF