In today’s podcast, I’m talking with long time integrative medical clinician and anti-aging expert Lynne Mielke, MD about her approach to bioidentical hormones and why the Precision Analytical DUTCH is her go-to test for assessing biHRT response.
It really takes courage to completely change course and walk away from a successful hospital medicine career. Dr. Brooke Stubbs did just that after realizing the pace and pressure of her work were costing her health. She found her way to lifestyle medicine, and that shift changed everything about how she practices—and how she lives. In our conversation, Brooke talks about what she’s learned along the way—how to build a concierge practice that actually works, set boundaries, create supportive systems, and price her services in a way that’s fair and sustainable. She also shares how Vibrant’s customizable panels have helped her provide consistent, comprehensive care. I love her honesty about learning through trial and error and her passion for building community. Her story is such a great reminder of what’s possible when we combine science, purpose, and heart in medicine. ~DrKF
When I sit down with Sergey Young, I’m always struck by the balance he brings. He’s deeply embedded in the future of longevity science, yet he champions the fundamentals we already know work: nutrition, exercise, sleep, purpose, and medical screening. For me, that’s a powerful reminder that as functional medicine practitioners, we already have the tools to help patients live longer, healthier lives. What excites me in this conversation is how Sergey shows us that the technologies on the horizon, including AI drug discovery, blood-based cancer tests, organ regeneration, and wearables, are making these solutions more affordable, more immediate, and more engaging for our patients. This isn’t just a distant dream. It’s a glimpse of where medicine is heading, and we are well positioned to lead the way. ~DrKF
Hair loss isn’t just cosmetic. It’s a visible marker of aging biology and a profound emotional burden, and I think this is even more true for women. The last time Carolina Reis Oliveira joined me on the podcast, we explored the OS-01 peptide for skin. This time, she’s back to share new research on how it can be applied to hair, not only outperforming minoxidil in clinical trials but also pointing us toward protocols that address stress, hormones, UV exposure, and the scalp microbiome. I love OneSkin’s deep commitment to science and the curiosity that drives their work, which is exactly what allows them to bring discoveries like this forward. This is the kind of science that changes the way we think about both aging and patient care. ~DrKF
This is the longevity conversation functional medicine providers need to hear. What struck me in each of these conversations is how deeply functional medicine already holds the answers we’re chasing in longevity science. We don’t need to reach for extremes. The tools we use every day—our frameworks, our lens, our root-cause approach—are longevity medicine. If you’re a clinician who’s felt unsure about where you fit in this rapidly growing space, I want this episode to remind you: you’re already in it. You’ll hear how leaders in our field are using the functional medicine matrix to slow cognitive decline, decode inflammatory pathways, and reframe aging itself as a process we can impact—intelligently and safely.
This conversation with Dr. Nir Barzilai is one of the most thought-provoking we’ve had on New Frontiers. His decades of research on centenarians, biological age, and the hallmarks of aging have shaped how we think about longevity—and what’s possible when we start targeting aging itself, not just individual diseases. We get into the science behind why some people live 20–30 years longer and healthier, and what it means to measure the biological age of individual organs. But we also hit a few sparks—especially when it comes to nutraceuticals and the role of metformin in prevention. I don’t agree with everything you’ll hear, and I followed up with Dr. Barzilai afterward to unpack some of the more provocative claims. We may just need a second round for this one… stay tuned.
I’ve been watching the science behind Calocurb evolve over the last year, and I have to say—this is one of the most exciting clinical tools I’ve seen emerge in the metabolic space in quite some time. A hops-derived compound that stimulates endogenous GLP-1, CCK, and PYY—without a prescription or injection? That’s a big deal, especially for patients struggling with appetite regulation, weight plateaus, or the aftermath of GLP-1 discontinuation.
Before we dive in—I just want to say thank you. Ten years of New Frontiers wouldn’t have been possible without your support, your curiosity, and your commitment to moving this field forward. I’m so excited to share this conversation with Romilly. ~ DrKF
This episode is a little different from what we usually cover on New Frontiers, but it’s one I couldn’t wait to bring to you. I’ve been thinking a lot about how we—as clinicians—are supposed to keep up in this era of high-throughput technology. We’re swimming in data: labs, multi-omics, diet logs… and an ever-growing stream from wearables. There’s just so much coming at us, and too often, we’re awash in a sea of information without adequate interpretive power.
I’ve been looking forward to sharing this conversation with you because it’s one I’m truly passionate about. Today, we’re diving into the DunedinPACE epigenetic clock with one of its creators, the brilliant Dan Belsky. It’s a tool I use regularly with my patients, and one that’s transforming how we approach aging and interventions. While this show is a bit more technical than usual, the science is fascinating, and the real-world applications are incredibly valuable. This isn’t just about theory—it’s about practical insights that can change how we measure aging and track the effectiveness of the treatments we offer. Stick with us, and you’ll walk away with actionable knowledge that can make a difference in your practice. ~DrKF