From time to time, Dr. Kara Fitzgerald invites selective guest contributors to submit content for publication on her website that aligns with her vision and mission, and high standards for quality and scientific rigor.

Targeting Immune Aging: New Findings from the MitoImmune Study on Urolithin A (Mitopure®)

Can Mitopure®, and its active ingredient Urolithin A, support an aging immune system? As we recognize immune aging as a primary driver of age-related disease, this question has taken on new clinical importance. The newly published MitoImmune study in Nature Aging provides the first rigorous clinical evidence to address this question. Conducted by researchers from Timeline, the Buck Institute for Research on Aging, and the lab of Professor.

The Power of a 10-Day Detox: A Functional Medicine Reset for Energy, Focus, and Epigenetic Balance

The Power of a 10-Day Detox: A Functional Medicine Reset for Energy, Focus, and Epigenetic Balance

As functional medicine practitioners, we know that nutrition and lifestyle are among the most powerful levers for preventing and reversing all chronic disease, from cardiovascular disease and hypertension to cancer and type 2 diabetes. Yet we also see firsthand how challenging it can be for patients to translate recommendations into sustained daily practice. Deeply ingrained habits don’t shift overnight. In fact, a meta-analysis of 20 studies involving more than 2,600 participants found that health-related habits typically take 2–5 months to form, which is far longer than the popular “21-day” myth suggests.

Treatment-Resistant Depression: Why Standard Care Fails and What to Do About It

Treatment-Resistant Depression: Why Standard Care Fails and What to Do About It

Despite a dramatic rise in antidepressant use in the United States since 1988, the number of Americans suffering from depression has not decreased. This leaves clinicians with a stark reality: more medication, without improvement. This reality raises the central question that inspired the Healing Depression Project: Is depression truly treatment-resistant, or are current treatments simply not effective?

Moving Beyond Glucosamine: The Future of Functional Joint Care

Moving Beyond Glucosamine: The Future of Functional Joint Care

Osteoarthritis (OA) is a debilitating, chronic joint disease affecting about 33 million adults in the United States. As the aging population grows and obesity rates climb, this number is expected to surge. By 2030, nearly 67 million Americans will be living with arthritis, with OA being the most prevalent form. OA is not just a condition of the joints – it’s a systemic burden that increases the risk of serious comorbidities such as cardiovascular disease, type 2 diabetes, and depression, significantly impairing quality of life and increasing healthcare costs.

What Urinary Hormone Metabolite Testing Tells Us about Estrogen Metabolism and Breast Cancer Risk

What Urinary Hormone Metabolite Testing Tells Us about Estrogen Metabolism and Breast Cancer Risk

Estrogen is a life-giving hormone with which modern humans have a complicated relationship. Over two decades ago, The Women’s Health Initiative (WHI) findings mistakenly reported that combined estrogen and progestin hormone therapy increased the risk of breast cancer, coronary heart disease, stroke, and venous thromboembolism in postmenopausal women. This led to a pervasive vilification of estrogen therapy that has affected generations of women.

Biohacking Your UV Defense: How Antioxidants Optimize Your SPF

Protecting your skin from UV radiation isn’t just about minimizing sunburns—it’s about slowing a significant accelerant of biological aging that triggers oxidative stress, immune suppression, and cellular senescence. While traditional sunscreens are a barrier to limiting UV exposure, they aren’t perfect alone. They can wash or rub off easily, degrade when exposed to heat and sunlight, and don’t address the downstream photodamage that continues long after exposure. That’s where antioxidants come in—they target oxidative stress, support cellular repair, and fortify your skin’s intrinsic UV defenses. Let’s explore the mechanisms of antioxidant-driven photoprotection and how integrating these compounds into your regimen can enhance skin longevity and resilience.

doctor working at a medical practice

How to Start and Grow Your Practice (for Clinicians, not MBAs!)

Starting and growing an integrative medical practice is a transformative journey that requires careful planning, commitment, and adaptability. Often, integrative and functional medicine providers are great clinicians when it comes to helping their patients, but feel inadequately prepared to run the business side of their practice. Dr. Linda Matteoli, at Origins Incubator, has the solution to this conundrum, walking physicians through the process to increase confidence, maintain authenticity, and achieve outcomes. The strategies they share in this article are valuable for all of us. – DrKF

Polyphenol-rich Winter Oatmeal

  We love this combination of creamy oats, sweet apples, and warming spices for a fall or winter breakfast. It also works with peaches instead of apples! Oats are rich in beta-glucans, a soluble dietary fiber that’s perfect in sweets, because it supports blood sugar balance and regulates lipids, like cholesterol. Cinnamon supports blood sugar…