From time to time, Dr. Kara Fitzgerald invites selective guest contributors to submit content for publication on her website that aligns with her vision and mission, and high standards for quality and scientific rigor.

Skin care. Hands in close-up

Why Skin Health is the Ultimate Test of Longevity

When you think about longevity tests, you might picture lipid panels and fasting blood glucose assessments. However, there’s one aspect of longevity you might not immediately consider: the health of your skin. From eczema and rosacea to premature lines and wrinkles, what’s happening on the surface is often indicative of underlying issues, including those that contribute to cardiovascular disease, dysbiosis, and mitochondrial dysfunction.

Beyond Beauty: Targeting Skin Longevity with Urolithin A

In the pursuit of wellness and longevity, skin health often mirrors the body’s internal state, serving as a visible testament to our overall well-being. Yet, traditional approaches to skincare have predominantly focused on treating the surface, neglecting the deeper cellular processes that fundamentally influence the skin’s aging and vitality. As we delve deeper into the science of longevity, a groundbreaking perspective emerges, spotlighting the crucial role of cellular and mitochondrial health not only in preserving the skin’s youthful appearance but also in maintaining the integrity of this critical organ. By shifting our focus beyond that of how we look, we can unlock new strategies for maintaining health and find a promising future where skincare transcends cosmetic concerns to embrace a holistic view of health and aging.

holiday decorations and snowstorm

Holiday Stress – What’s in Your FxMed Toolbox?

We’ve made it successfully through the Thanksgiving rush. But do you or your patients need a set-and-refresh to make it through the rest of the holidays? The holidays are supposed to be full of cheer, family, friends, good food and good feelings, but that’s often not the case. Beyond the specter of seasonal colds and flu, patients may seek our help for another reason in December: stress. Stress can affect a multitude of biological systems, from cardiovascular to the respiratory system—but for the acute seasonal stressors like travel, family, and dietary changes, we most often see its effects on the central nervous system and the digestive system. Tension headaches, occasional trouble sleeping, indigestion and irregularity are common culprits that we can easily address with small lifestyle changes and supplementation.

Case Studies: Targeting Gut Health in Two Very Different Patient Scenarios

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Food sources of fiber

Fiber – Are You Getting Enough to Reap its Amazing Benefits?

Only 5% men and 9% of women are getting the recommended daily amount of fiber in the United States.[1] That’s almost 90% of the population not consuming enough fiber! To put this into perspective, in 2017–18 most Americans averaged 8.1 grams of fiber for each 1,000 calories, or just 58 percent of the recommended 14 grams per 1,000 calories. Insufficient fiber intake is associated with a myriad of chronic diseases. Let’s dive into what fiber is, why it is so important, and how you can get more of it in your diet!

A Step-Change in Our Approach to Mitochondrial Care with Urolithin A

Over the last decade, there has been an explosion of research looking at bioenergetics (energy metabolism) and the role our energy generators – the mitochondria – play in human health and longevity. In functional medicine, we’ve long been aware of bioenergetics – the need to “tend to our patient’s mitochondrial health,” and as such, we readily employ a litany of nutrients – from CoQ10 to carnitine and lipoic acid and others – whenever we deem them indicated. There have not been, however, many nutrients to blast onto the bioenergetics center stage with quite the impressive force as the postbiotic rock star Urolithin A. With studies published in top-tier journals such as Nature and Cell – and with 11 (yes, eleven) compelling human clinical trials – if this compound hasn’t made it to the top of what you’re using for patients (and taking yourself), read on.

man coughing with seasonal cold

Reducing the impact of the seasonal cold with Pelargonium sidoides 1X (EPs 7630)®

Acute illnesses like seasonal colds carry a heavy socioeconomic burden and impact livelihood in many ways, taking a great toll on society including children, families, and the medical community. This results in increased direct costs (e.g., clinic visits, drug consumption, hospitalizations), indirect costs (such as absenteeism at work and reduced productivity), and intangible costs (e.g., pain, suffering and impaired quality of life).

Women, Midlife and Longevity: Considerations for Successful Aging

Midlife is an extremely active time epigenetically. Pro-inflammatory genes tend to become hypomethylated and get ramped up, tumor-suppressor genes can become progressively more silenced, genes that code for antioxidant and detoxification enzymes such as glutathione transferase (which also happens to be an important tumor-suppressor gene!) also get dialed down, and genes that promote cancer (known…


Pesky Weight Gain During Menopause? Address Hormonal Changes

Weight gain is one of the most frequently seen complaints during perimenopause and menopause. In this blog we will explore why that is and how the female body changes during this magical and yet confusing life stage. Menopause and perimenopause typically begin for women around the age of 45 – 55 years. We start to notice changes in our bodies prior to the loss of our cycle including hot flashes or night sweats, change in frequency and how heavy our periods can be, and changes in mood. Perhaps the most unsettling for females is the change in weight and body mass distribution: clothes fit differently, your body feels different, your capacity at the gym and with physical activity feels futile! And this usually happens with little change to your current nutrition or activity routine.