Scientific Papers Retracted from One of the World’s Most Prestigious Journals

Last week, the prestigious medical journal, The Lancet, retracted two COVID-19-related papers. One of those papers had reported on negative effects of hydroxycloroquine as a potential treatment option, leading to much controversy over the use of the drug. The reason for the retraction? Surgisphere Corporation, the company providing the underlying database of information that was…

Food Labeling

FDA Food Labeling Regulations are Relaxed During COVID

Food label regulations have been temporarily loosened by the FDA in response to supply disruptions reported by the food industry. What does this mean for consumers? Importantly, consumers should know that food manufacturers are allowed to make formulation changes, including omissions or substitutions, of ‘minor’ ingredients without making note of those changes on the label.…

Dementia

Having Two ApoE4 Gene Alleles Appears to Double the Risk for Severe COVID-19

ApoE4 is known for increasing the risk for dementia. New analysis of UK data suggests that it may also increase the risk for more severe outcomes from COVID-19 – double that of those with the ApoE3 gene variants. This finding held true independently of pre-existing dementia, cardiovascular disease and type 2 diabetes. More research is…

Detecting Nutritional Deficiencies in Sweat – A New Possibility

Biosensors that provide realtime feedback on health-related parameters are considered profoundly useful tools for optimizing health status and encouraging adherence to healthier activities. A new wearable device now does this for vitamin C. The device contains the enzyme ascorbate oxidase, which on contact with vitamin C (ascorbic acid) changes the electrochemical current flow. Given the…

Inflammation resolution is a key strategy for escalating COVID-19 symptoms – a new paper and free DrKF webinar replay

From the folks that brought us Specialized Pro-resolving Lipid Mediators (SPMs), comes a new peer-reviewed paper that highlights the potential for SPMs in addressing pro-inflammatory cytokine production and cytokine storm in COVID-19. SPMs stimulate macrophage-mediated clearance of cellular debris and reduce pro-inflammatory cytokine levels. They also promote anti-viral B cell antibodies and other white blood…

Organs targeted by ACE-2-utilizing viruses like COVID-19

This infographic from Scientist illustrating the many organs that the virus can gain entry to using ACE2 or TMRPSS2 receptors (definitive evidence for viral presence in the various organs is still being established, but the presence of the receptors provides a road map for investigation). Certainly this influences the wide variety of COVID presentations we…

Can Unconventional Immunomodulatory Agents Help Alleviate COVID-19 Symptoms and Severity?

ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SARS coronavirus 2, or SARS-CoV-2) is the cause of the respiratory infection known as COVID-19. From an immunopathological standpoint, coronaviruses such as SARS-CoV-2 induce increased levels of a variety of T-helper 1 (Th1) and inflammatory cytokines and chemokines, including interleukin-1 (IL-1), IL-6, CCL2 protein, and CXCL10 protein. In…