Dead Mitochondria Might Be Fueling Cardiovascular Aging — Here’s The Fix

Dysfunctional Mitochondria Are Fueling Cardiovascular Aging — Here’s The Fix

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This is a really exciting conversation with Dr. Davide D’Amico from Timeline, where we’re taking a closer look at Urolithin A and heart health. It should come as no surprise that this mitochondrial wonderkin of a nutrient is showing promise here—especially when you consider that 40% of the heart’s weight is mitochondria. That’s an extraordinary factoid, and one that really shifts how we think about aging in the cardiovascular system.

Why Human-Centered AI Is the Future of Medicine & Mental Wellness

Why Human-Centered AI Is the Future of Medicine & Mental Wellness

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This episode is a little different from what we usually cover on New Frontiers, but it’s one I couldn’t wait to bring to you. I’ve been thinking a lot about how we—as clinicians—are supposed to keep up in this era of high-throughput technology. We’re swimming in data: labs, multi-omics, diet logs… and an ever-growing stream from wearables. There’s just so much coming at us, and too often, we’re awash in a sea of information without adequate interpretive power.

Legal Pitfalls That Could Destroy Your Practice & How to Avoid Them

Legal Pitfalls That Could Destroy Your Practice & How to Avoid Them

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In many ways, the legal side of functional medicine can feel like the Wild West—uncertain, unregulated, and full of risks. The reality is, we all want to have our practices legally buttoned up, but navigating the legal landscape can feel overwhelming—and expensive. What Scott Rattigan, creator of Functional Lawyer, shares in this episode is a real game-changer. He not only breaks down the complexities of the legal side of things but also offers real solutions for us—solutions that can make sure we’re covered without the stress and uncertainty that often comes with it. Whether you’re just starting out or growing your established practice, you’re going to get actionable insights on how to avoid common legal pitfalls, protect your practice, and actually move forward with confidence. It’s a topic that’s been an unmet need for so long, and I’m so excited to bring this to you. ~DrKF

Why You’re Aging Faster Than You Think & How to Slow It

Why You’re Aging Faster Than You Think & How to Slow It

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I’ve been looking forward to sharing this conversation with you because it’s one I’m truly passionate about. Today, we’re diving into the DunedinPACE epigenetic clock with one of its creators, the brilliant Dan Belsky. It’s a tool I use regularly with my patients, and one that’s transforming how we approach aging and interventions. While this show is a bit more technical than usual, the science is fascinating, and the real-world applications are incredibly valuable. This isn’t just about theory—it’s about practical insights that can change how we measure aging and track the effectiveness of the treatments we offer. Stick with us, and you’ll walk away with actionable knowledge that can make a difference in your practice. ~DrKF

Can We Regrow Joints and Reverse Inflammaging? New Research Suggests YES

What New Research Says About Cartilage Regeneration and Joint Longevity

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Osteoarthritis affects millions—chronic pain, limited mobility, and a dramatically reduced quality of life. But what if the answer isn’t just about treating the joint, but the inflammation driving the damage? In today’s episode, Kiran Krishnan, a leading microbiologist and advisor to Calroy Health Sciences, unveils a groundbreaking approach to joint health. He explains how chronic low-grade inflammation fuels osteoarthritis and accelerates joint degeneration. Even more exciting? Cartigenix, a revolutionary product combining unique extracts from celery seed and Boswellia, is showing real potential to regenerate cartilage, reduce pain, and improve mobility. Kiran also dives into the fascinating link between osteoarthritis and cardiovascular disease, why supporting liver health plays a crucial role in optimizing joint repair and how preventative strategies like Cartigenix can protect your joints before they start to decline. This episode could change everything you know about managing inflammation and joint health—don’t miss it!

The Shocking Truth About Chronic Illness: How to Reset Your Nervous System & Slow Aging

The Truth About Chronic Illness: How to Reset Your Nervous System & Slow Aging

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We’ve all had patients struggling with chronic conditions like long COVID, fibromyalgia, Lyme disease, and chronic fatigue. Despite all the tools in our functional medicine toolkit, there’s still something missing. How can we truly help them? I’m excited to have Ashok Gupta is back on the New Frontiers podcast to offer a new take on that healing from chronic illnessquestion. He explains that how many chronic diseases stem from a malfunction in the brain’s threat detection system, where the body overreacts to perceived threats, triggering immune, nervous system, or mood responses, . This creatinges a vicious cycle. Ashok shares how retraining the brain and calming the nervous system can reset the body’s response to chronic stress and presents the growing body of research supporting thehis Gupta Program, including new subjective measurements like CRP showing its impact. What excites me most is the potential for this approach to help some of my toughest-to-treat patients. With more studies emerging, I’m increasingly hopeful this could be a game-changer. It’s a conversation you won’t want to miss! ~DrKF

What Your Mitochondria Wish You Knew: A Look Inside Cutting-Edge Mitochondrial Science

Hidden Mitochondria Problems Are Accelerating Your Age & Draining Your Health

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What if the key to reversing chronic disease, slowing cognitive decline, and boosting energy lies in the tiny powerhouses inside your cells—and we’ve finally found a way to protect them? We know mitochondria power our cells, but did you know they also create oxidative stress as they generate energy? Protecting mitochondrial health is critical—but most antioxidants can’t reach inside the mitochondria where protection is needed most—until now. MitoQ, a scientifically advanced, mitochondria-targeted antioxidant developed by visionary researchers in New Zealand penetrates mitochondria up to 90%, offering protection where it’s needed most. In this episode with Dr. Siobhan Mitchell, we dive into how MitoQ is transforming the way we tackle chronic disease, inflammation, and cognitive decline. From improving heart health to supporting brain function, MitoQ is changing the game. It’s something I’m using personally and recommending to most of my patients. Listen in to discover how this powerful tool can help you support your patients at the cellular level—before symptoms even appear. ~DrKF

Next-Gen Alzheimer’s Testing: The Power of p-Tau 217 and Blood-Based Biomarkers

p-Tau 217: The Breakthrough Biomarker Revolutionizing Early Alzheimer’s Detection

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Join me for a fascinating conversation around an exciting breakthrough in dementia detection that’s offering real hope for early intervention. Dr. Hans Frykman, Chief Scientific Officer at Neurocode Laboratories, is here to share groundbreaking insights into cutting-edge biomarkers that can identify Alzheimer’s disease before symptoms even appear. What’s even more fascinating is how these same tools are revealing neuroinflammation caused by infections, including COVID, Lyme disease, and mold exposure—issues that are incredibly relevant in functional medicine today. The assays Dr. Frykman and his team have developed are transforming the way we think about diagnosing and addressing neurodegeneration. We’re talking about a potential game-changer that allows us to intervene earlier, reverse damage, and ultimately improve the trajectory of these conditions. This is an extraordinary time in science and medicine, and the work we’re discussing today is at the forefront of it all. Don’t miss out on how this could reshape your practice. ~DrKF

Cutting Edge Interventions For Patients with Adverse Food Reactions with Dr. Tom Fabian

Cutting-Edge Metabolomic Testing for IBS, Longevity, and Metabolic Health

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We’re witnessing an exciting shift in how we understand gut health and disease—and it’s all thanks to the powerful metabolites produced by the microbiome, like short-chain fatty acids (SCFAs) and secondary bile acids. In today’s episode, Dr. Tom Fabian shares groundbreaking insights into how these postbiotics influence intestinal barrier integrity, immune balance, and even muscle regeneration. These compounds are also connected to key processes like glucose metabolism and healthy aging. What’s truly fascinating is how this science is opening up new frontiers in treating IBS, metabolic conditions, and chronic gut issues. With the upcoming launch of Diagnostic Solution Laboratories’ StoolOMX test an add-on to the GI-MAP, we now have a tool to measure these metabolites in clinical practice, making personalized and effective treatments more attainable. This is a pivotal moment in functional medicine that you don’t want to miss.

Exposomics and Precision Medicine: Redefining Chronic Disease with Environmental Insights

A Fresh Take on Exposomics: Resiliency Factors That Offset Environmental Risks

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In this episode, we’re diving into exposomics—one of the most cutting-edge fields in environmental medicine. We in the functional medicine space have long embraced this approach that focuses on the lifelong effects of environmental exposures, from the prenatal period on, and how these exposures shape our health over time. I’m thrilled to have Drs. Robert and Rosalind Wright with us, pioneers in this field at Mount Sinai to share their research exploring how environmental factors, from lead and air pollution to social stress, can influence chronic diseases like asthma, obesity, Alzheimer’s, and autism.