Targeting Cellular Senescence for Healthier, More Youthful Skin

Targeting Cellular Senescence for Healthier, More Youthful Skin

Today, we’re diving deep into a breakthrough in skincare science that has caught my attention—OneSkin’s OS-01 peptide. This episode explores how OS-01 targets cellular senescence, the core of aging, potentially transforming skin health.I’m particularly impressed by OneSkin’s commitment to rigorous research and evidence-based results. Their approach not only aims to rejuvenate skin but also enhances its natural radiance and elasticity. This could be a significant advancement for individuals managing aging skin or conditions like atopic dermatitis.

Unlocking Inflammation Resolution: The Power of Specialized Pro-Resolving Lipid Mediators with Ashley Koff

Resolving Chronic Inflammation using SPMs: A Two-Phase Approach with Ashley Koff RD

If you’re looking to elevate your approach to inflammation and pain management, this episode is for you. Today, we dive into a fascinating conversation with registered dietitian Ashley Koff. We discuss the intricate role of specialized pro-resolving mediators (SPMs) and their potential applications in various health conditions, from inflammation and pain management to neurodegenerative diseases and autoimmune disorders. We also explore the nuances of gamma-linolenic acid (GLA) and its importance in functional medicine, particularly for women in perimenopause and menopause. If you’re curious about the latest insights on using SPMs in conditions like Lyme arthritis, chronic infections, and even concussions, this episode is packed with valuable information. We’ll also touch on practical strategies for incorporating these powerful molecules into your therapeutic protocols, ensuring your patients receive the most comprehensive care possible.

Cutting Edge Interventions For Patients with Adverse Food Reactions with Dr. Tom Fabian

Challenging Food Reactions? Addressing the Gut Microbiome and More with Dr. Thomas Fabian

In this episode, we’re diving into the forefront of understanding adverse food reactions, a topic that’s experiencing a significant paradigm shift in both perception and treatment strategies. Our guest, Dr. Thomas Fabian, a leading expert on the role of the microbiome, will shed light on the underlying pathophysiology of these reactions. We’ll discuss specific gut microbes and microbial functions identified in recent studies, providing concrete examples of their involvement in various types of adverse food reactions.Join us as we navigate through the latest advancements in immune tolerance understanding, microbial variances in the gastrointestinal tract, and the profound influence of GI physiology on adverse food reactions.Stay tuned for an enlightening discussion that will undoubtedly shape the future of functional medicine practice. ~DrKF

Urolithin A and GLP-1 Agonists: A winning combination with Dr. Anurag Singh

Mitigating Muscle Loss from GLP-1 Agonists, with Dr. Anurag Singh

I am paying attention closely to research coming from the largely untapped world of postbiotic compounds and their essential role in human physiology. I have had the honor to talk quite a few times with Dr. Anurag Singh, and always the clinical (and preclinical) research that he and his team are up to looking at postbiotic wunderkind urolithin A (a compound produced by GI bacterial action on precursor compounds found in pomegranate) are thrilling, powerful and illustrate how wildly important these compounds are in human physiology

Reducing Senescent Cell Accumulation for Enhanced Longevity with Dr. Greg Kelly

Targeting Senescent Cells? Dose and Timing Matters – with Dr. Greg Kelly

I’m thrilled to welcome you to a truly fascinating discussion on the cutting edge of longevity medicine. In this episode, I sit down with the brilliant Dr. Greg Kelly to explore the complex world of cellular senescence and its profound implications for our aging process. We delve into the challenges of identifying these aging cells and the exciting research that’s paving the way for more accurate biomarkers. I’m particularly excited to share with you Dr. Kelly’s insights on how simple lifestyle changes, such as incorporating regular exercise and mindful caloric intake, can significantly reduce the accumulation of senescent cells. We also discuss some groundbreaking interventions, including the use of senolytic agents like quercetin, dasatinib, and piper longumine, and how they’re revolutionizing our approach to longevity.

Unraveling PCOS and Fertility: Debunking Common Misconceptions with Dr. Tara Harding

Unraveling PCOS and Fertility: Debunking Common Misconceptions with Dr. Tara Harding

Fellow clinicians, gear up for an enlightening dive with Dr. Tara Harding, a vanguard in the realm of women’s health and fertility. Renowned for her exceptional work as a family nurse practitioner and fertility coach, Dr. Harding brings a wealth of knowledge from her battle against infertility and medical gaslighting, all while breaking barriers and fostering a supportive community for those navigating the complex journey of infertility. This conversation not only highlights innovative diagnostic tools like Mira but also delves into the nuances of managing conditions like PCOS and endometriosis. Dr. Harding’s personal and professional journey is a beacon of hope and empowerment, underscoring the significance of comprehensive care in women’s health. Prepare to be inspired by her dedication to revolutionizing fertility care and advocating for patient empowerment.

Advanced Metabolomics: Identifying the Metabolic Signature for Aging with Betsy Redmond, Ph.D., MMSc, RDN

Advanced Metabolomics: Identifying the Metabolic Signature for Aging with Betsy Redmond, Ph.D., MMSc, RDN

As functional practitioners, we’re compelled to understand the intricate changes in the aging journey that fuel the diseases we strive to prevent. The emergence of omics data, particularly metabolomics, marks a pivotal moment, and I’m thrilled to welcome back Dr. Betsy Redmond, a senior education specialist at Diagnostic Solutions Laboratory and a cherished friend, to New Frontiers. In this episode, we delve into the transformative power of metabolomics, emphasizing pathways over isolated metabolites for profound insights and more effective interventions. Welcome to Medicine 3.0, where we correct imbalances, identify metabolites linked to healthy aging, mood, gut health, and more, providing actionable steps to enhance both healthspan and lifespan. Plus, we’ll unravel some surprising insights from my own results! Join us for a wealth of valuable pearls to use in your practice. ~DrKF

Urolithin A: Postbiotic Rockstar on the Longevity Stage

Beyond Mitochondrial Health: Can Urolithin A Slow Down Aging?

In the realm of bioenergetics, few nutrients have burst onto the stage with the impressive force wielded by the postbiotic rock star—Urolithin A. In today’s episode I’m honored to be joined by the brilliant Dr. Chris Rinsch, co-founder of Amazentis / Timeline, as we delve into the profound impact of this remarkable substance and unravel the scientific intricacies behind the microbiome’s transformation of polyphenols from our diet into Urolithin A. You’ll quickly understand why it’s emerging as a potent force in cellular health and longevity.

Breast Health and Beyond: A Practitioner’s Guide to Functional Testing

Breast Health and Beyond: A Practitioner’s Guide to Functional Testing

Over 270,000 new cases of breast cancer are diagnosed each year in the US. And while BRCA mutations often get the most press, there are other, potentially more critical factors we can address. Today, Dr. Ruth Hobson joins us to delve into the realm of breast health, shedding light on both modifiable and non-modifiable risk factors, and sharing real-life strategies for supporting our patients. We dive into a range of essential topics, from dietary and lifestyle influences to the ongoing debate around Hormone Replacement Therapy (HRT), and venture into the world of functional tests to evaluate hormones and metabolites crucial for comprehensive breast health. We’ll uncover the intricate connection between gut health and breast health – Did you know that breast tissue has its own microbiome?!? – and examine how inflammation, peripheral fat, and methylation impact cancer risk. Bring a pen and paper, this is a deep dive into the hormones and breast health that you won’t want to miss. ~DrKF

Revolutionizing Healthcare: Rupa Health's Mission to Empower Practitioners and Patients

From Complex to Accessible: Streamlining Functional Medicine Labs

If you’re a regular listener, you’ve undoubtedly heard me sing the praises of Rupa Health numerous times, and there’s a compelling reason for it! Rupa has taken the FxMed world by storm, introducing a product that has quickly become indispensable. In this episode of New Frontiers, I’m joined by Dr. Kate Kresge, Head of Medical Education at Rupa, to delve into the invaluable tools that Rupa offers to make Functional Medicine accessible to everyone. Dr. Kate’s passion for naturopathic medicine was ignited by her own struggles as a chronically ill child. Her transformative experience inspired Dr. Kate to pursue a career in naturopathic medicine and change the standard of. When Rupa invited her to join their team, it felt like the perfect fit. Tune in for this highly valuable conversation to hear how Rupa Health is reshaping the healthcare landscape with consistent innovation, offering specialty labs and educating newcomers to functional medicine. Learn about their time-saving solutions that enable practitioners to allocate more time with patients and enhance outcomes for a broader audience.