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Integrative Protocols: Focus on Senolytics, Cell Senescence, and the Role of Telomerase Activation

Colleagues, if you’ve been following me for any time, you’ve heard me speak frequently about aging as the top driver of chronic disease. In today’s interview, I dive into evidence-based integrative protocols to prevent and reverse the aging process. My guest, Dr. Joseph Cleaver MD, is a Fellow of the American Board of Anti-aging and Regenerative Medicine, is board-certified in internal medicine, a rheumatologist, on faculty at A4M and MMI and has authored and published a wealth of research and scholarly articles. He founded Paradigm Wellness Medical Group in Dallas and Sonoma Valley, California, AND he is Medical Director at Boutique Wellness in Winston, North Carolina. Folks, you’ll want to be ready to take notes during this interview, as Dr. Cleaver shares his personalized senolytic protocols specific to patient phenotypes. Listen, share, and leave a starred rating, if you wouldn’t mind! Thanks for listening. ~DrKF

Episode 69: Sponsored | Telomere Integrity: What Clinicians Need to Know with Dr. Joseph Raffaele

Sponsored |The Best Biomarker of Aging: What Clinicians Need to Know

I am particularly fascinated by new advances in testing biological age and how these biomarkers relate to disease risk. My podcast guest today is Dr. Joseph Raffaele MD, a leading expert, researcher, and clinician on the topic of biological aging and telomeres. We talked last year on New Frontiers, and I’m psyched to continue the conversation!

This time, Dr. Raffaele and I explore the various tests he uses to determine physiological age and disease risk, and go big into how senescent T cells and infections, such as cytomegalovirus, increase COVID-19 risk, particularly in a younger, seemingly healthy population. You’re going to love this enticing convo on the role of aging as it relates to disease and COVID-19 risk, and might find some great take-away clinical pearls to use in your own practice. Settle in, this is a good one, and let me know what you think by leaving a review or comment! ~DrKF

Got Good Guts? Clinically Effective Applications for SIBO, SIFO, and Dysbiosis

Episode 78: Sponsored | Got Good Guts? Clinically Effective Applications for SIBO, SIFO, and Dysbiosis

Dr. Jocelyn Strand is the Director of Clinical Education at Bio-Botanical AND a great clinician herself. Prepare yourself: this is a very actionable podcast for clinicians using bioB. And for me, a huge pearl on refractory SIBO was unaddressed oral microbiome! In this episode of New Frontiers, learn how Dr. S addresses sibo using BB products. To test or not to test?

The Business of Functional Medicine: Secrets for Success for your own FxMed Practice

Episode 76: Sponsored | The Business of Functional Medicine: Secrets for Success for your own FxMed Practice

Dr. Jeff Gladd is a brilliant Fx/integrative physician who is PASSIONATE about all things Fx business. Learn about FS’s integrated EMR, our Clinic Immersion and Fx Residency programs, with top tips for building your brand. And so much more. Check out the show notes for loads of links, references, downloads and more, and be sure to leave a review wherever you listen to New Frontiers! As always, thank you for listening! ~DrKF

Innovations in Clinical Laboratory Testing with Dr. Michael Chapman

Episode 74: Sponsored | Innovations in Clinical Laboratory Testing with Dr. Michael Chapman

A work horse laboratory in any functional medicine practice is stool testing. But really gleaning the best insight into our patient’s clinical picture can be tough. What do all of these commensal organisms really suggest? How do they correlate with the inflammatory findings? Of the bell weather bugs (like akkermansia) how can we increase levels? Is there ANY place for microscopy (O&P) and culture in today’s high throughput Omics world?

Cornerstone Interventions for GERD with Victoria Albina

Episode 71: Sponsored | Cornerstone Interventions for GERD with Victoria Albina

Take a second and think about this: what clinical presentation would prompt you to prescribe cognitive behavioral coaching, breathwork or meditation? Did GERD make your list? Along with gentle, but powerful botanicals and nutraceuticals (IT’s Motility Agitator, DGL Chewables, Heartburn Advantage), these are cornerstone interventions for GERD in the practice of Victoria Albina, NP, MPH.

Episode 69: Sponsored | Telomere Integrity: What Clinicians Need to Know with Dr. Joseph Raffaele

Episode 69: Sponsored | Telomere Integrity: What Clinicians Need to Know with Dr. Joseph Raffaele

Are you thinking about age management with your patients these days? I am. And I’m thinking about it regarding myself, quite frankly. To that end, I just had a tour-de-force conversation with clinician researcher Joe Raffaele, MD. Can we halt, or even reverse, the biological aging process? There are an extraordinary number of variables to consider here, but the take-home appears to be YES.

New Hope for Fibromyalgia Patients with Erik Lundquist, MD

Episode 66: Sponsored | New Hope for Fibromyalgia Patients with Erik Lundquist, MD

Fibromyalgia is a tricky disorder to treat. Patients struggle with chronic pain and fatigue, and practitioners often struggle to find effective interventions. Dr. Erik Lundquist is pioneering research into novel treatments for fibromyalgia. In a new study, he investigates the use of specialized pro-resolving lipid mediators (SPMs) for fibromyalgia patients.

Episode 62: Methionine Metabolism and Methylation with Dr. David Quig

Episode 62: Sponsored | Methionine Metabolism and Methylation with Dr. David Quig

Methylation and sulfuration are complex processes and assessing them in practice takes skill, knowledge, and consideration of multiple genes and other factors. Lucky for us, we have the incredible Dr. David Quig from Doctor’s Data on the podcast today, getting into the nitty-gritty about assessing methylation in clinical practice.

Episode 60: Dutch™ Research And Validation In Peer-reviewed Journal Article

Episode 60: Dutch™ Research and Validation In Peer-Reviewed Journal Article

In today’s podcast, I chat with my friend and fellow laboratory geek Mark Newman, founder and president of Precision Analytical (creators of DUTCH), about his recent publication [Evaluating urinary estrogen and progesterone metabolites using dried filter paper samples and gas chromatography with tandem mass spectrometry (GC–MS/MS)], smartly published in an open access – and reputable – journal, BMC Chemistry, so it’s available to all, free of charge.