Breast cancer may affect as many as 1 in 8 women. It’s important for patients and providers to understand the role that estrogen detoxification plays in breast cancer so that they can make more informed mitigation and treatment decisions.
DetailsWhen a team of scientists from EPFL, the Swiss Federal Institute of Technology in Lausanne, set out to thoroughly study the health benefits of pomegranates, they discovered something truly remarkable – the power of a postbiotic nutrient, Urolithin A (UA) to promote cellular health and longevity. For the past 15 years, Urolithin A has been one of the most well-researched longevity molecules. Over 300 studies, 11 of which are clinical trials, show impressive benefits in UA’s ability to target some of the key biological hallmarks of aging. These same scientists and doctors developed the first and only clinically tested Urolithin A formulation (more on that below!)
DetailsWhen we’re young, building a skin care routine is relatively simple: a face wash, moisturizer and sunscreen will do the trick. But as we grow older and develop visible signs of aging skin, choosing from the overwhelming array of mature skin care products like anti-aging creams, serums, and treatments often feels like an impossible task. What can we trust to actually work? It’s easy to get lost in new trends like 10-step skincare routines, but try to look past marketing and prioritize your skin’s health above all else. As our largest organ and first line of defense against environmental aggressors, our skin can have an enormous impact on our overall body health. A truly effective skin care routine should support your skin’s health first and improve the way it looks as a result. That’s where OneSkin comes in.
DetailsIn the fields of functional medicine, functional longevity and epigenetics, research is moving quickly – and so spending time delving into the scientific literature and discussing new findings with other experts in the field is essential. Last month, a new paper landed on my desk, published in the leading journal Cell. It lays out a…
DetailsWhat oral health can tell us about gluten reactivity Can discolored teeth, canker sores, and geographic tongue be caused by reactions to gluten? We know that the second largest and most diverse microbiome is found in the oral cavity and that poor oral health is associated with multiple conditions, including diabetes and heart disease. Should we…
DetailsIf you’re a regular reader/follower, you’ll know I frequently share new research related to epigenetics and biological aging that I think is useful to know. I have also collected here what I hope is a useful “round up” of that research over the past year. Read on to learn more and make sure you haven’t…
DetailsThis might just have been our most exciting year yet here at Dr. Kara Fitzgerald! With the launch of three books through major publishing houses, authored by my team and myself, we have barely had a moment to touch ground. Yet, delivering high value content in the functional medicine and longevity space, across all channels,…
DetailsMetabolomics testing provides a window into a wide range of physiological processes that can be disrupted in illness and corrected with diet, nutrition, and lifestyle interventions. When combining metabolic markers with stool testing, a more complete picture of a patient’s metabolic and immune systems emerges.
DetailsHow Much Should We Eat For Optimal Health & Longevity? Plus my thoughts on combining with Younger You epinutrient targets About a month ago, I podcasted with Valter Longo, PhD, a highly respected scientist and director of the Longevity Institute at the University of Southern California. Of course, our conversation hit on protein, something…
DetailsThe function of the digestive tract is essential for proper function of almost every biological system in the body. Hormone metabolism and endocrinology is no exception to this rule. In fact, the connection is so strong with estrogen, that there is a term to describe it in the literature – the estrobolome.
DetailsSince my last writing, I have continued my studies on female hormones and hormone replacement therapy and I have dug deep into the male literature on testosterone (T) and testosterone therapy (TTh). Similar to my quest to learn everything about female hormones and hormone therapy, the same holds true for testosterone and TTh in males.
DetailsCardiovascular conditions are one of the most common disorders of modern times. Testing for cholesterol as a potential modifiable risk factor for heart disease is a common part of many functional medicine providers’ clinical practices. Recently, at Rupa Health we wrote about the latest innovations in cholesterol testing such as measuring ApoB-containing lipoproteins and genetic differences in intracellular cholesterol production or gut absorption. In this article we will go beyond cholesterol to discuss the other critical tests for heart health.
DetailsHave you heard about epinutrients? Surprisingly, they’re barely mentioned in research papers and yet they are potent epigenetic regulators (i.e. they control how our genes are expressed). And I think it’s time to shine some light on these longevity superstars. But first, have you ever wondered why food has such powerful effects on our health…
DetailsMany of you know about methylation and how problems with this process are linked to heart disease, diabetes, Alzheimer’s, attention deficit hyperactivity disorder (ADHD), autoimmune disease, and autism. But did you know that methylation problems may also be involved in other more surprising areas of your health? In this article, we’ll dive into those other lesser-known consequences of faulty methylation and what you can do about it. But first, a refresher course on what methylation is and how the MTHFR mutation is involved in methylation problems.
DetailsUpdated December 9, 2022 “Age is just a number,” as the saying goes – but which number, exactly? Of course, you can count to this year from the one you were born in, but that’s far from the most relevant one. You’ve likely had one or more double-takes upon learning a new friend was five…
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