Short-Chain Fatty Acids: Strengthen the Gut-Brain Health Connection with Butyrate
All SCFAs have wide-ranging therapeutic benefits, but in this article we’ll focus on butyrate as a therapeutic agent for gut and brain health. Butyrate is the food for the colonocytes, the thin layer of cells that comprises the lining of the large intestine. Within the intestinal environment, it protects and supports the mucosa, gut motility, and the commensal bacteria of the colon. Although butyrate is largely present in the gut, it can also have effects on the brain via the gut-brain axis, as well as by lowering inflammation, stabilizing DNA structure, and sequestering harmful metabolic by-products like ammonia.
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