Early Cytokine Signatures Predict COVID Severity and May Guide Interventions

According to this new Nature paper, those with severe COVID are spiking higher cytokine signatures early on. This would suggest value in testing, including possibly IFN-gamma (see below), and addressing it early through anti-inflammatory diet and lifestyle, as well as targeted anti-inflammatory nutraceutical interventions. This is, of course, a ‘standard’ approach used in Functional Medicine,…

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More Robust Data Now Emerging on Vitamin D and COVID

COVID patients with poor prognosis have significantly lower serum levels of vitamin D compared to those with good prognosis, according to new data from a systematic review that pulled data from seven previous studies into its meta analysis. A total of 1,368 COVID-19 patients were included in the pooled results. Those with poor prognosis had…

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New Data on Effects of Ketogenic Diet in Breast Cancer

This is an important new trial providing for the use of ketogenic diets in certain cancers, coauthored by our valued colleagues Dr. Thomas Seyfried and Miriam Kalamian. This randomized, controlled trial of 60 patients with locally advanced or metastatic breast cancer and planned chemotherapy found that those receiving the 12-week ketogenic diet intervention experienced a…

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Are Children Major COVID-19 Spreaders? Evidence is Mixed But Leans Against School Closures

It’s an understandable concern based on past experiences with other viral infections, such as influenza and measles, where children are known to be significant transmitters. However, according to several recent publications, infected children are less significant spreaders of COVID-19 and their own source of infection may more likey be symptomatic or pre-symptomatic adults. Adults who…

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BRCA Gene Mutations and Hypermethylation – The Flavonoid Potential

BRCA1/2 gene mutations, not included in direct-to-consumer genetic testing, are associated with higher rates of ovarian cancer (17-44%) and breast cancer (69-72%). A new study argues that routine testing for these gene vulnerabilities could prevent up to an estimated 2,666 cases of breast cancer per million women, and up to 449 ovarian cancer cases per…

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Diet Alters Period Pain and Duration

Diet has a strong influence on a woman’s cycle. In our clinic, we have successfully used dietary and lifestyle strategies to help individuals with painful, heavy, periods and other types of menstrual and hormonal concerns.

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No Further Trials Needed to Determine if Omega-3 Fats Reduce the Risk of Cardiovascular Disease and Death

This new meta-analysis indicates that ‘no further trials are needed to better evaluate the efficacy of PUFAs in preventing death related to CVD”. A total of 100,609 patients were analyzed. Reduction in mortality due to cardiovascular issues was statistically significant with a relative risk of 0.937, CI 0.88-0.98, P=0.018. Is it time to put this decades-long debate to bed? We think so.

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