A new Harvard-led analysis finds that COVID-19 patients that live in areas with higher air pollution, such as New York City, have experienced a higher death-rate from the infection than those who lived in areas with cleaner air.
There has been quite a bit of kerfuffle about the workhorse nutrient vitamin D. We are getting pinged daily on whether it should be used or avoided in the COVID19 pandemic. I believe this question was fueled by a recent write-up mentioning an in vitro study showing that D can up-regulate certain cytokines.
Zinc is needed to slow viral RNA replication and it also regulates inflammatory cytokines. Anosmia and ageusia, as reported in COVID-19 and also common symptoms of flu, are classic signs of zinc defficiency.
Coronavirus testing is providing a fundamental lesson for all of us about how medical lab testing works – there are no tests that are 100 percent accurate.
Let’s take a quick look at what we know about COVID-19. Then I’ll talk about what it means for us all, how we can best support ourselves and our communities, some novel treatments, and some specific techniques for reducing stress and boosting immunity in this incredibly stressful time.
For those physicians called to the hospital front lines, MedCram has a free video series on mechanical ventilation. From MedCram: “We understand that medical professionals (and students) that don’t have significant experience with mechanical ventilation may be called upon to help ventilator management teams in critical care settings. And clinicians with extensive ventilator experience may want a refresher or a tool to aid in teaching mechanical ventilation strategies to other clinicians.” They also have another class on ARDS. Also free.
A few additional treatment possibilities in COVID19 (SARS Cov-2) addressing furin-like cleavage and pyroptosis (caspacin-1 activation of inflammasome NLRP3)
The cytokine storm seen in SARS Cov1 and Cov2 might be due to chronic pyroptosis activation. However, known activators of NLRP3 in SARS-CoV differ from CoV2. While SARS Cov1 and COVID19 are genetically very similar, the extraordinarily high rate of infectivity of COVID19 is unique. Prepublication research suggests the cause might be a unique furin-like cleavage site on the spike protein of Cov2 that was absent in Cov1.
For those interested, here is the link to Nick Ortner’s page for free tapping meditations for anxiety, stress, and fears around the Coronavirus. You can also check out the science and research.
While working as a psychiatrist at a maximum-security hospital, John Cannell screened his patients for vitamin D and found that all had very low levels.
Test kits for COVID-19 are still scarce. For clinicians looking for potential sources, here are two: