melanin-covid

Melatonin May Offer Significant Protection from COVID Infection, and especially for African Americans

Supplementing with melatonin may decrease the likelihood of contracting COVID, particularly among African Americans. Researchers analyzed data from an observational study of over 26,000 people from a COVID-19 registry at the Cleveland Clinic Health System and found that melatonin use is associated with a 52% reduced likelihood of a positive SARS-CoV-2 test in African Americans.…

COVID case brief using a Functional approach

From DrKF – What’s especially interesting in this case is the less common symptom of oral ulcerations, responded well to frequent saline/iodine gargles. We are seeing several cases like this demonstrating a rapid resolution of symptoms and no complications in healthy individuals.   Case clinician: Romilly Hodges CNS Presentation: 45 y/o F in good general…

SARS

A few additional treatment possibilities in COVID19 (SARS Cov-2) addressing furin-like cleavage and pyroptosis (caspacin-1 activation of inflammasome NLRP3)

The cytokine storm seen in SARS Cov1 and Cov2 might be due to chronic pyroptosis activation. However, known activators of NLRP3 in SARS-CoV differ from CoV2.  While SARS Cov1 and COVID19 are genetically very similar, the extraordinarily high rate of infectivity of COVID19 is unique. Prepublication research suggests the cause might be a unique furin-like cleavage site on the spike protein of Cov2 that was absent in Cov1.