Elevated furin levels are not only associated with Covid-19 but also linked to comorbidities including diabetes, obesity, and hypertension – perhaps one reason why these comorbidities are linked with worse COVID-19 outcomes. In this peer-reviewed publication, Dr. Kara Fitzgerald discusses the role of furin proteases in Covid-19 and how dietary, lifestyle, natural and pharmaceutical interventions aimed at inhibiting furin may prevent the development of critical symptoms.