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Dr. Kara Fitzgerald received her doctorate of naturopathic medicine from National College of Natural Medicine in Portland, Oregon.

Dr. Fitzgerald is actively engaged in clinical research on the DNA methylome using a diet and lifestyle intervention developed in her practice. The first publication from the study focuses on reversal of biological aging and was published 04-12-2021 in the journal Aging

Dr. Fitzgerald received her doctorate of naturopathic medicine from National College of Natural Medicine in Portland, Oregon. She completed the first CNME-accredited post-doctorate position in nutritional biochemistry and laboratory science at Metametrix (now Genova) Clinical Laboratory under the direction of Richard Lord, Ph.D. Her residency was completed at Progressive Medical Center, a large, integrative medical practice in Atlanta, Georgia.

Dr. Fitzgerald is the lead author and editor of Case Studies in Integrative and Functional Medicine and is a contributing author to Laboratory Evaluations for Integrative and Functional Medicine and the Institute for Functional Medicine (IFM)’s Textbook for Functional Medicine. With the Helfgott Research Institute, Dr. Fitzgerald is actively engaged in clinical research on the DNA methylome using a diet and lifestyle intervention developed in her practice. The first publication from the study focuses on reversal of biological aging and was published 04-12-2021 in the journal Aging. A consumer book and application-based program with DNA methylation assessment are scheduled for release 01-2022.

Dr. Fitzgerald is on faculty at the Institute for Functional Medicine, and is an Institute for Functional Medicine Certified Practitioner. She regularly lectures internationally and is in private practice in Sandy Hook, Connecticut.

  • Doctorate of naturopathic medicine from National College of Natural Medicine in Portland, Oregon
  • Post-doctorate position in nutritional biochemistry and laboratory science at Metametrix
  • Residency was completed at Progressive Medical Center
  • Lead author and editor of Case Studies in Integrative and Functional Medicine
  • Contributing author for IFM’s Textbook of Functional Medicine
  • Contributing author for Laboratory Evaluations for Integrative and Functional Medicine
  • Contributing author for Oxford University Press Integrative Gastroenterology, 2nd edition
  • Co-researcher, in collaboration with the Helfgott Institute at NUNM, Methylation Diet & Lifestyle Study now published in the journal Aging. For more information about the program and to order the book, published by Hachette, click here.
  • Faculty member at Institute for Functional Medicine
  • Institute for Functional Medicine Certified Practitioner (IFMCP)
  • Approved supervisor for Certified Nutrition Specialist candidates seeking experience hours
Dr. Kara Fitzgerald on Instagram

Did you know about 114.4 million Americans have unhealthy blood sugar levels!?* That’s about one-third of the entire country. If any of the above things sound familiar, it could be a direct result of your fluctuating blood sugar levels.

And since diet remains at the forefront of blood sugar management, optimizing nutrition by using specific foods is a key intervention.

One such functional food is apple cider vinegar (ACV). It has been shown to help the body process sugar in the blood, so you can avoid that blood sugar roller coaster and all the side effects that come with it.

There are many ways to incorporate ACV into your diet, including supplements such as @Paleovalley’s Apple Cider Vinegar Complex which has the added benefits of turmeric, cinnamon, and other blood-sugar balancing foods.

And you can get 15% OFF today by heading to the link in my bio!


Remember to check out my discussion with Dr. Joseph Raffaele (@raffaelemd) on this episode of #NewFrontiersInFunctionalMedicine. We discuss how chronic viral infections might be accelerating our aging, the telomere position effect, and how to measure your levels of senescent T cells.

Check it out!

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This Saturday (and as the holiday season swings into full gear) I am HERE for you. You don't need an excuse to take a "me day": stress accelerates biological aging and thus makes all the diseases of aging more likely.

If you're feeling stressed treat yourself. Take a walk, do a face mask, do yoga, enjoy a long bath, etc. And as you are doing your preferred activity take a second to appreciate that you are actually reversing your biological age at the level of your DNA. Learn more about the science in my new book Younger You:

Are chronic viral infections accelerating our aging? Could they also be contributing to neurodegeneration? And is immune-senescence at the root of aging?

On this episode of #NewFrontiersInFunctionalMedicine, Dr. Joseph Raffaele (@raffaelemd) sits down with me to discuss immune risk phenotypes, epigenetic aging markers, and why the virome is as important as the microbiome. You’ll definitely want to listen to this one!

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So much is intuitive and easily adoptable in Younger You. There's JUST ONE real downside for people - cutting back on wine. So let's start with the controversial part first. Is wine healthy? Contrary to popular perception, the research on it is complex, but the answer tends to be that the negatives actually outweigh the positives. Grapes (and resveratrol) ARE great for you, but the alcohol content lessens their benefits. It does so by inhibiting the enzymes used in the methylation and folate cycles, which results in a potentially significant reduction of SAMe (the body’s main methyl donor), lowers folate absorption, and directly inhibits the enzymes that methylate our DNA.

Does that mean you need to give up wine forever? Of course not! But you shouldn't be treating it as a health food, either. What we actually find is that you can counteract some of the negative effects by pairing it with some of our methylation superstar foods (beets, liver, etc). Thus, red wine is acceptable in small amounts as part of our everyday program.

So that's it, that's the bad news. The good news? You can literally reverse DNA damage and marks of biological aging with a coordinated plan that is flexible and adaptable to your lifestyle. In a study we reversed bioage by 3 years in just 8 weeks, and that reversal may help you avoid, lessen, or reverse the many related diseases of aging. Learn more (link in bio):

Have you ever tried to take a shot of apple cider vinegar? It’s not pleasant.

And it could actually be harmful to your teeth and esophagus!

But that doesn't mean you have to miss out on the fat-burning, craving-crushing benefits of ACV!

With @Paleovalley Apple Cider Vinegar Complex, you can harness all of its powers without the harsh taste or potential damage.

Plus, ACV Complex includes 4 additional superfoods: Turmeric, Ginger, Lemon, and Cinnamon! When all of these ingredients come together you have a natural, fat-burning powerhouse.

And you can get 15% OFF today at the link in bio!

An extraordinary new preprint from David Sinclair’s lab at Harvard demonstrates this, amazingly enough. In a mouse model, scientists pushed aging forward by inducing pro-aging changes to the epigenome, and then they flipped the epigenetic information around in the same mice, restoring youth. WOW. They caused aging, then reversed aging, all via epigenetic changes.

These findings come at just the right time when the world of anti-aging and epigenetics is rapidly evolving and gaining attention. And I think this is validating for all of us in this field.

A key feature of our Younger You program is massaging epigenetic expression towards optimal via diet and lifestyle. I believe this is why our participants got significantly younger in such a short period of time. And this study could offer us clues on the underlying molecular mechanisms for these impressive results.


In the US, most people spend the last 16 years of their lives (16 years!!) with multiple chronic diseases and on multiple medications. I cannot imagine this fate (although I see it everywhere).

I don’t want drug companies, hospitals, and extended care facilities taking my daughter's inheritance, so I can “live” but not participate in life.

I am taking the pledge to live my best, longest, fullest life now, and forever. For me, my family, for Isabella. That's why I'm committed to using smart DNA methylation to prevent the diseases of aging.

Our Younger You program is, with the focus on bio age reversal, setting its sights on creating a new generation of healthy centenarians!

Join us:

Vitamin C is more than an immune booster - it also plays an important role in neurotransmitter synthesis and can thus support restful sleep and stress resilience.*

Before you rush to buy the first immune-boosting product you see on the shelf this flu season, note that not all vitamin C supplements are created equal.

Most of them contain the synthetic form of vitamin C, called ascorbic acid, that is sourced from GMO corn and then harshly processed with acids like acetone. These products are better than nothing… but when it comes to your health you deserve better than that.

Our friends at @Paleovalley have developed an all-natural Essential C Complex which contains 3 natural sources of vitamin C that are gently processed to preserve the nutrients - there is nothing else like this on the market.

And you can get a 15% OFF discount at the link in bio!

*PMID: 33371359

Suffering from chronic fatigue? Don’t miss this FASCINATING discussion between guest host, Dr. Patrick Hanaway, and @alexhowardtherapy on #NewFrontiersInFunctionalMedicine! Topics include: the primary maps for decoding and recovering from fatigue, the different subtypes of people in the fatigue population, and how the fatigue recovery process actually works.

This one you won’t want to miss!

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Nearly every C product on the market is synthetic ascorbic acid, and not the full spectrum vitamin C that you find in food. And while they still offer some health benefits, whole foods-sourced C may be even better.

Food-derived C, such as that found in the acerola berry, may be better absorbed and utilized, possibly due to the presence of phytonutrients.*

And that’s exactly what @Paleovalley’s Essential C Complex is derived from: acerola, camu camu and amla berries. These 3 natural sources are minimally processed to preserve nutrient quality, hence providing 450mg of vitamin C per serving.

Claim an exclusive 15% OFF discount at the link in bio!

*PMID: 30150795

We all know that exercise has many benefits for our health, but did you know that those benefits could likely be due to changes in DNA methylation?

Multiple studies now point towards epigenetic modification as the underlying mechanism of the health benefits of exercise. By acting through various pathways such as DNA methylation, histone modification, and non-coding RNA expression, exercise may prevent inflammation, mitigate disease risk, and lead to healthy metabolic remodeling.

And as we have found in our own epigenetic aging trial, a multimodal intervention approach that includes physical activity can be a powerful anti-aging tool. This is why daily exercise is an essential component of our 3 Years Younger program.

Read the full literature review here:

50,000,000 people in the US have been diagnosed with at least one of over 120 known autoimmune conditions.

You’re likely either one of them or have someone close to you who is.

That's why I was excited to join the Autoimmune Masterclass, which airs the weekend of Nov. 13th/14th – and features 22 of the world’s leading doctors, practitioners, researchers, and experts on all things autoimmune.

The best part? It’s totally free to watch. You can sign up here (link in bio) →

Sneezing. Such a common thing which we all experience, yet science knows so little about… until now. A recent mouse study has identified the molecular pathway behind our sneezing reflex. Scientists from Washington University have pieced together the neural circuit behind sneezing, tracing its journey from nose to brain. Driven by her own family’s struggle with seasonal allergies, lead researcher Liu and her team made the ground-breaking discovery of neuromedin B (NMB) – a signaling molecule that activates the region of the brain responsible for exhalation. NMB is released by nasal sensory neurons following stimulation by irritants such as histamine and without it, there would be no sneezing reflex. Because sneezing can significantly contribute to pathogen transmission, researchers hope this new understanding will help find alternative ways to mitigate and slow down the spread of infectious respiratory diseases.

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We have known for some time now that the benefits of moderating carbohydrates extend beyond blood sugar management and now new research shows that a lower-carb diet improves blood lipids including the resistant Lp(a).

The clinical trial by the Boston Children’s Hospital found that a low-carb, high-fat diet significantly improved markers for cardiovascular disease, including a 14.7% reduction in lipoprotein(a) and a 5-point decrease in lipoprotein insulin resistance (LPIR) score which measures the size and concentration of various lipoprotein subfractions.

In the study, 147 healthy adults consumed low-, moderate- or high-carb diets for 20 weeks. In the low-carb group, 20% of calories came from carbohydrates and 60% from fats, compared with 60% of calories from carbohydrates and 20% from fats in the high-carb, low-fat group.

Interestingly, the low-carb group consumed a higher amount of saturated fats (21% of total energy intake) compared with the high-carb group (7% of total energy intake). These findings suggest that restricting carbohydrates in the diet, and not saturated fats, can have beneficial effects on blood lipid profiles and may lower CVD risk.

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