Episode 63: Best Strategies to Prevent Cognitive Decline with Grain Brain author and neurologist Dr. David Perlmutter
In this podcast you’ll hear:
- The potential pitfalls of Alzheimer’s drugs
- The relationship between exercise and increased synapses, synaptogenesis, and neuroplasticity
- The ketogenic diet as a therapeutic intervention for mitochondriopathy
- Understanding Parkinson’s as a pancerebellar event that is accompanied by other manifestations of inflammation, like seborrhea, arthritis, and constipation
- Understanding Alzheimer’s as a multifactorial event
- The powerfully damaging role of dietary sugar in brain health
- How to dose MCT oil for patients; benefits of MCT oil for mitochondriopathy,
- The benefits of beta-hydroxybutyrate in terms of its histone deacetylase activity.Dr. Perlmutter’s optimal range for patients’ fasting glucose
- Understanding and interpreting fasting insulin levels in relation to fasting glucose and HbA1c
- Coffee’s relationship to ketone levels in the body
- The relationship between fasting, the ketogenic diet, and exercise intensity
- Why improving insulin sensitivity is the main goal in nutrition strategies for preventing cognitive decline
- Dr. Perlmutter’s recommended supplements
- The relationship between APOE-4 positive status, insulin resistance, and beta-amyloid accumulation in the brain
- How to choose and dose a DHA supplement
- The lab tests Dr. Perlmutter recommends
- The relationship between PCOS, brain energy utilization, and potential for cognitive impairment in older age
