COVID patients with poor prognosis have significantly lower serum levels of vitamin D compared to those with good prognosis, according to new data from a systematic review that pulled data from seven previous studies into its meta analysis. A total of 1,368 COVID-19 patients were included in the pooled results. Those with poor prognosis had an average vitamin D difference of -5.12 nmol/L (2.05 ng/mL), p=0.012, suggesting that even small corrections could have a beneficial impact on outcomes.
According to the authors: “Despite vitamin D promoting the expression of several inflammatory cytokines via T-cell inactivation and interferon-gamma activation25, it simultaneously down-regulates pro-inflammatory markers interleukin-6 and tumor necrosis factor-alpha the two key cytokines involved with the development of the “cytokine storm” that precedes ARDS.”
Kara Fitzgerald, ND, received her doctor of naturopathic medicine degree from the National University of Natural Medicine in Portland, Oregon. She completed the first Counsel on Naturopathic Medicine-accredited post-doctorate position in nutritional biochemistry and laboratory science at Metametrix Clinical Laboratory under the direction of Richard Lord, PhD. Her residency was completed at Progressive Medical Center, a large, integrative medical practice in Atlanta, Georgia.
Dr. Fitzgerald is the lead author and editor of Case Studies in Integrative and Functional Medicine and is a contributing author to Laboratory Evaluations for Integrative and Functional Medicine and the Institute for Functional Medicine (IFM)’s Textbook for Functional Medicine. With the Helfgott Research Institute, Dr. Fitzgerald is actively engaged in clinical research on the DNA methylome using a diet and lifestyle intervention developed in her practice. The first publication from the study focuses on reversal of biological aging and was published 04-12-2021 in the journal Aging. She has published a consumer book titled Younger You as well as a companion cookbook, Better Broths and Healing Tonics and has an application-based Younger You Program, based on the study.
Dr. Fitzgerald is on the faculty at IFM, is an IFM Certified Practitioner and lectures globally on functional medicine. She runs a Functional Nutrition Residency program, and maintains a podcast series, New Frontiers in Functional Medicine and an active blog on her website, www.drkarafitzgerald.com. Her clinical practice is in Sandy Hook, Connecticut.
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