gene-expression

Epigenetic Reprogramming Restores Age-Related Vision Loss in Mice

Intriguing new research shows that it is possible to reverse age-related cellular dysfunction in vivo, specifically age-related vision loss. This suggests that modifying epigenetic expression is a powerful tool to counteract the damage of aging. The study published in Nature sought to reset the epigenome and DNA methylation patterns by expressing transcription factors, which help…

vitamin D

Vitamin D Deficiency Increases Risk of Severe COVID Infection & Mortality

More research confirms that maintaining optimal vitamin D levels is extremely important for reducing the risk of infection with SARS Cov-2. A six-week observational study of 154 people published in Nature found that 97 percent of individuals with severe COVID-19 had vitamin D deficiency (mean concentration was 14 ng/mL) compared to 33 percent of people…

vegan-jama

JAMA Article Attributes Dietary Benefits to Veganism But Misses Other Potential Contributors

The results from a newly-published trial on the effects of a dietary intervention in overweight adults are impressive: 14 lbs weight loss, increased insulin sensitivity, a 19.3 mg/dL reduction in total cholesterol, 15.4 mg/dL reduction in LDL cholesterol, and reduced fat distribution in the liver and muscles (associated with reduced risk for fatty liver and…

cancer therapy

Nearly Half of New Cancer Therapies Approved by FDA Lack Randomized Clinical Trial Evidence & Only Prolong Life by Weeks

A large number of cancer therapies are approved by the FDA without randomized clinical trials and only increase median survival by 2.4 months, according to a new review article published in the Journal of the American Medical Association (JAMA). This may come as a surprise and disappointment considering the urgent goals of cancer research to…

military-arthritis

Military Environmental Exposure Linked to Rheumatoid Arthritis in Veterans

Environmental toxins have been shown in several studies to be a potential trigger for immune dysfunction and autoimmunity. Now new data, from ex-military personnel, adds to that evidence base. In this recent study, published in Arthritis & Rheumatology, U.S. veterans exposed to military burn pits and waste disposal were found to harbor more antibody markers for rheumatoid…

Green tea

Green Tea & Coffee Consumption Reduces Risk of Death in Type 2 Diabetes

A new study from Japan suggests people with type 2 diabetes who consume both green tea and coffee (quite a methylation adaptogen cocktail) have a lower risk of death. By a significant amount. Researchers studied nearly 5,000 patients over a five-year period and found that drinking either beverage alone helped reduce the risk of mortality (from any cause): Drinking…

covid data

Data Emerge on “Long” COVID Characteristics and Risk Factors

Long COVID is now recognized as a post-viral syndrome of chronic debilitating symptoms that can last for months. Similar post-viral syndromes that have been observed follow other infections such as influenza, pneumonia, Epstein-Barr virus, and HIV. New data from a recent study by Kings College London of 4 million individuals in the United Kingdom indicates that: It’s relatively…