This April marked an important milestone for me and my team with the publication of our groundbreaking clinical trial on reversing biological age through diet and lifestyle. And since then, quite a number of research articles have been published on this very same topic.
DetailsIf you’re a regular reader/follower, you’ll know I frequently share new research related to epigenetics and biological aging that I think is useful to know. I have also collected here what I hope is a useful “round up” of that research over the past year. Read on to learn more and make sure you haven’t…
DetailsA normally developing child developed regressive autism at 18 months. The child lost the ability to speak, make eye contact, and to interact socially.
DetailsMany of you know about methylation and how problems with this process are linked to heart disease, diabetes, Alzheimer’s, attention deficit hyperactivity disorder (ADHD), autoimmune disease, and autism. But did you know that methylation problems may also be involved in other more surprising areas of your health? In this article, we’ll dive into those other lesser-known consequences of faulty methylation and what you can do about it. But first, a refresher course on what methylation is and how the MTHFR mutation is involved in methylation problems.
DetailsOnline marketing is an opportunity to engage, converse and create a name for your legacy
DetailsSometimes a simple low FODMAPs diet, or a course of prescription or botanical antimicrobials, is enough to shift a case of SIBO.
DetailsI was hanging out at Whole Foods Market (WFM) last night. It was the grand-opening day. Kind of embarrassing to admit such a thing would get me going, but it did.
DetailsThe cytokine storm seen in SARS Cov1 and Cov2 might be due to chronic pyroptosis activation. However, known activators of NLRP3 in SARS-CoV differ from CoV2. While SARS Cov1 and COVID19 are genetically very similar, the extraordinarily high rate of infectivity of COVID19 is unique. Prepublication research suggests the cause might be a unique furin-like cleavage site on the spike protein of Cov2 that was absent in Cov1.
DetailsAs you know, here at drkarafitzgerald.com we like to push the boundaries of what we know, and sometimes this means being a little contrarian. In this blog, our Nutrition Director, Romilly Hodges CNS takes us on a tour of some of the emerging research on Th17 prompted by a new paper in the journal Cell, that postulated a reduction in Bifidobacteria may mediate some of the benefits of a ketogenic diet for epilepsy by reducing Th17.
DetailsIt got me thinking about why it is that calicos can only be females and how much the interesting genetics of this cat can teach us about our genes and…
Details[Additionally, (and off topic) but an important point none-the-less, I am very concerned about the chronic use of antihistamines in my allergic patients…
DetailsWaaaaaay before Atkins put the butter-and-bacon version of the ketogenic diet on the map (based on the 1958 work of Pennington), very low carb diets were…
DetailsI admit it. I’ve harvested a scientific nugget or two from the Daily Mail. Not long ago, sandwiched between a story on toast and the five-second rule, and a selfie of Zac Efron eating a worm, was this…
DetailsThe importance of oral health as required for systemic health is well-accepted in the functional world. However, with up to 77% of American adults over 30 years of age suffering from periodontitis, there is an urgent need to actively address oral health as a routine part of clinical practice.
DetailsOver the last decade, there has been an explosion of research looking at bioenergetics (energy metabolism) and the role our energy generators – the mitochondria – play in human health and longevity. In functional medicine, we’ve long been aware of bioenergetics – the need to “tend to our patient’s mitochondrial health,” and as such, we readily employ a litany of nutrients – from CoQ10 to carnitine and lipoic acid and others – whenever we deem them indicated. There have not been, however, many nutrients to blast onto the bioenergetics center stage with quite the impressive force as the postbiotic rock star Urolithin A. With studies published in top-tier journals such as Nature and Cell – and with 11 (yes, eleven) compelling human clinical trials – if this compound hasn’t made it to the top of what you’re using for patients (and taking yourself), read on.
DetailsThere has been a lot of published research lately around the role of our skin’s microbiome on overall immune health as well as the impact bacterial dysbiosis has on different diseases. The bacteria Cutibacterium acnes (C. acnes) — one of the most abundant strains of bacteria in most people’s facial microbiome — has long been associated with acne lesions. But, how does acne occur and how does our microbiome impact it?
DetailsWe in functional medicine have long been aware that children can start out with a clearly identified food allergy. As the child ages, the primary allergic symptoms fade and some other clinically relevant presentation appears in its place. For example: we’ll see a classic milk allergy in infancy — often as milk colitis.
DetailsWhen a nutritional supplement has been studied in more than one dose for one or more indications, it’s imperative to decide what the best starting dose should be in a typical case. This seems simple; however, even reviewing the same data, clinicians can come to opposing conclusion and thus, dosing strategies.
DetailsEverything old is new again. It was just a few years ago that a promising drug to treat Alzheimer’s disease was stopped in its tracks owing to phase III…
DetailsAnd so it goes with the global, ready-dissemination of other infections, too, including Ebola, Zika and…severe influenza strains: “An infection in all but the most remote corner of the world can make its way to a major city in a day or less.”
DetailsAre you enriching their lives with good, healthy food choices and lifestyle habits or are you angering your trillions of guests, pushing them towards causing disease? I wrote my thesis in medical school on stealth infections, where I concluded that health had much to do with how well we tended our microbial garden… I was…
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