Reducing Senescent Cell Accumulation for Enhanced Longevity with Dr. Greg Kelly

Targeting Senescent Cells? Dose and Timing Matters – with Dr. Greg Kelly

I’m thrilled to welcome you to a truly fascinating discussion on the cutting edge of longevity medicine. In this episode, I sit down with the brilliant Dr. Greg Kelly to explore the complex world of cellular senescence and its profound implications for our aging process. We delve into the challenges of identifying these aging cells and the exciting research that’s paving the way for more accurate biomarkers. I’m particularly excited to share with you Dr. Kelly’s insights on how simple lifestyle changes, such as incorporating regular exercise and mindful caloric intake, can significantly reduce the accumulation of senescent cells. We also discuss some groundbreaking interventions, including the use of senolytic agents like quercetin, dasatinib, and piper longumine, and how they’re revolutionizing our approach to longevity.

Unraveling PCOS and Fertility: Debunking Common Misconceptions with Dr. Tara Harding

Unraveling PCOS and Fertility: Debunking Common Misconceptions with Dr. Tara Harding

Fellow clinicians, gear up for an enlightening dive with Dr. Tara Harding, a vanguard in the realm of women’s health and fertility. Renowned for her exceptional work as a family nurse practitioner and fertility coach, Dr. Harding brings a wealth of knowledge from her battle against infertility and medical gaslighting, all while breaking barriers and fostering a supportive community for those navigating the complex journey of infertility. This conversation not only highlights innovative diagnostic tools like Mira but also delves into the nuances of managing conditions like PCOS and endometriosis. Dr. Harding’s personal and professional journey is a beacon of hope and empowerment, underscoring the significance of comprehensive care in women’s health. Prepare to be inspired by her dedication to revolutionizing fertility care and advocating for patient empowerment.

Advanced Metabolomics: Identifying the Metabolic Signature for Aging with Betsy Redmond, Ph.D., MMSc, RDN

Advanced Metabolomics: Identifying the Metabolic Signature for Aging with Betsy Redmond, Ph.D., MMSc, RDN

As functional practitioners, we’re compelled to understand the intricate changes in the aging journey that fuel the diseases we strive to prevent. The emergence of omics data, particularly metabolomics, marks a pivotal moment, and I’m thrilled to welcome back Dr. Betsy Redmond, a senior education specialist at Diagnostic Solutions Laboratory and a cherished friend, to New Frontiers. In this episode, we delve into the transformative power of metabolomics, emphasizing pathways over isolated metabolites for profound insights and more effective interventions. Welcome to Medicine 3.0, where we correct imbalances, identify metabolites linked to healthy aging, mood, gut health, and more, providing actionable steps to enhance both healthspan and lifespan. Plus, we’ll unravel some surprising insights from my own results! Join us for a wealth of valuable pearls to use in your practice. ~DrKF

Urolithin A: Postbiotic Rockstar on the Longevity Stage

Beyond Mitochondrial Health: Can Urolithin A Slow Down Aging?

In the realm of bioenergetics, few nutrients have burst onto the stage with the impressive force wielded by the postbiotic rock star—Urolithin A. In today’s episode I’m honored to be joined by the brilliant Dr. Chris Rinsch, co-founder of Amazentis / Timeline, as we delve into the profound impact of this remarkable substance and unravel the scientific intricacies behind the microbiome’s transformation of polyphenols from our diet into Urolithin A. You’ll quickly understand why it’s emerging as a potent force in cellular health and longevity.

Breast Health and Beyond: A Practitioner’s Guide to Functional Testing

Breast Health and Beyond: A Practitioner’s Guide to Functional Testing

Over 270,000 new cases of breast cancer are diagnosed each year in the US. And while BRCA mutations often get the most press, there are other, potentially more critical factors we can address. Today, Dr. Ruth Hobson joins us to delve into the realm of breast health, shedding light on both modifiable and non-modifiable risk factors, and sharing real-life strategies for supporting our patients. We dive into a range of essential topics, from dietary and lifestyle influences to the ongoing debate around Hormone Replacement Therapy (HRT), and venture into the world of functional tests to evaluate hormones and metabolites crucial for comprehensive breast health. We’ll uncover the intricate connection between gut health and breast health – Did you know that breast tissue has its own microbiome?!? – and examine how inflammation, peripheral fat, and methylation impact cancer risk. Bring a pen and paper, this is a deep dive into the hormones and breast health that you won’t want to miss. ~DrKF

Revolutionizing Healthcare: Rupa Health's Mission to Empower Practitioners and Patients

From Complex to Accessible: Streamlining Functional Medicine Labs

If you’re a regular listener, you’ve undoubtedly heard me sing the praises of Rupa Health numerous times, and there’s a compelling reason for it! Rupa has taken the FxMed world by storm, introducing a product that has quickly become indispensable. In this episode of New Frontiers, I’m joined by Dr. Kate Kresge, Head of Medical Education at Rupa, to delve into the invaluable tools that Rupa offers to make Functional Medicine accessible to everyone. Dr. Kate’s passion for naturopathic medicine was ignited by her own struggles as a chronically ill child. Her transformative experience inspired Dr. Kate to pursue a career in naturopathic medicine and change the standard of. When Rupa invited her to join their team, it felt like the perfect fit. Tune in for this highly valuable conversation to hear how Rupa Health is reshaping the healthcare landscape with consistent innovation, offering specialty labs and educating newcomers to functional medicine. Learn about their time-saving solutions that enable practitioners to allocate more time with patients and enhance outcomes for a broader audience.

Mark Newman: Maximizing Hormone Health With The DUTCH Test

Mark Newman: Maximizing Hormone Health With The DUTCH Test

In this episode, I have the pleasure of interviewing Mark Newman, the president and founder of Precision Analytical, the company behind the revolutionary DUTCH test. Mark is a true pioneer in the field of hormone testing, and in our conversation, we delved into the latest developments in this rapidly evolving field. We discussed how the DUTCH test has expanded to include additional markers, providing even more comprehensive insights into hormone health. During our conversation, we also addressed the controversy surrounding saliva testing for hormone analysis. Mark shed light on the limitations of this method and why the DUTCH test offers a more accurate and reliable alternative. I’m sure you’ll find this interview as fascinating as I did, and it will be super helpful for identifying the best forms of hormone testing for your patients. So, without further ado, let’s dive into this enlightening conversation with Mark Newman. ~DrKF

Mastering Cardiovascular Longevity: Glycocalyx & Biohacking for Optimal Heart Health

Mastering Cardiovascular Longevity: Glycocalyx & Biohacking for Optimal Heart Health

Vascular health is fundamentally essential to longevity and health span, and that’s why I’m thrilled to be welcoming Dr. Michael Twyman to New Frontiers. Trained as an invasive cardiologist, Dr. Twyman has made the shift to a more preventative approach, moving beyond traditional cath lab results to focus on the health of the 60,000 miles of blood vessels that carry vital blood, oxygen and nutrients to every organ in the body, with hopes of reaching patients before they reach the end stages of disease.

Measuring Metabolites of Dysbiosis and Gut Function to Create Targeted Interventions

Measuring Metabolites of Dysbiosis and Gut Function to Create Targeted Interventions

As we gain insight into microbiome impact on our health, we need accurate tests that tell us not only what and how much is there, but also which metabolites, or post-biotics created that can have downstream effects. So today I’m thrilled to welcome the brilliant Dr. Erika Ebbel Angle from Ixcela Labs to discuss their metabolomic testing that can do just that. We’ll discuss the 11 key markers, the value of a blood sample over urine, and the impact of endurance sports and chronic stress on health markers as revealed by the test. And we also chat about my own results, how impressed I was by the insight provided – and how they clearly identified changes I could make to improve my markers. Listen and take notes — I know I did! ~DrKF

Disrupting Anti-Aging Skincare by Targeting Senescent Cells

Disrupting Anti-Aging Skincare by Targeting Senescent Cells

Imagine accurately determining the status of your skin’s age to tell whether it is younger or older than your chronological age, and then use this technology to determine whether expensive anti-aging serums and creams are effective, or actually causing more harm than good. Amazing, right? This is precisely the technology today’s guest, Dr. Carolina Reis and her fellow stem cell biologists at OneSkin created. I think you will find this interview fascinating on so many levels – I know I sure did! After creating their skin clock, the OneSkin team discovered peptide OS1, which targets senescent cells, one of the root mechanisms of aging, and is being shown in current studies to have a positive effect on hydration, firmness, elasticity, and the skin barrier. Listen as Dr. Reis explains the science and ongoing studies exploring the possible benefits of OS1 for the skin microbiome, hair loss, inflammation, and overall health. ~DrKF