Mapping the Placental Methylome: The Key to Early Autism Intervention with Dr. Janine LaSalle

Towards Predicting Autism in Utero with Dr. Janine LaSalle

Hold onto your hats, folks. We’re taking a deep dive into game-changing research with Dr. Janine LaSalle, epigeneticist extraordinaire. With autism rates increasing at an alarming rate, it’s been a huge struggle to really put our fingers on anything for diagnostics or prediction. Dr. LaSalle is on a mission to change that. She’ll walk us through her ground-breaking research around mapping the placental methylome, why it can be used as a surrogate marker for the brain, and how using methylation signatures provides insights into interventions that could potentially correct these issues in utero. Simply amazing!

Cutting Edge Interventions For Patients with Adverse Food Reactions with Dr. Tom Fabian

Challenging Food Reactions? Addressing the Gut Microbiome and More with Dr. Thomas Fabian

In this episode, we’re diving into the forefront of understanding adverse food reactions, a topic that’s experiencing a significant paradigm shift in both perception and treatment strategies. Our guest, Dr. Thomas Fabian, a leading expert on the role of the microbiome, will shed light on the underlying pathophysiology of these reactions. We’ll discuss specific gut microbes and microbial functions identified in recent studies, providing concrete examples of their involvement in various types of adverse food reactions.Join us as we navigate through the latest advancements in immune tolerance understanding, microbial variances in the gastrointestinal tract, and the profound influence of GI physiology on adverse food reactions.Stay tuned for an enlightening discussion that will undoubtedly shape the future of functional medicine practice. ~DrKF

Microbiome Reset: Building Childhood Resilience with Dr. Elisa Song

Smart, Actionable Strategies for Childhood Resilience, with Dr. Elisa Song

I’m delighted to welcome back Dr. Elisa Song, a respected colleague and pioneer in pediatric functional medicine. Today, we’re delving into the critical intersection of the gut microbiome and pediatric health. In today’s landscape, families are confronted with daunting challenges. Between the 3000 chemicals hiding in ultra-processed foods, alarmingly high sugar content (sometimes as much as 14 teaspoons in a single drink!), and the pervasive presence of antibiotics in our food supply, it’s no surprise that we’re seeing negative changes in the microbiome, worsening metabolic health, increased allergies, autoimmune disease, and neurodevelopmental issues.

Urolithin A and GLP-1 Agonists: A winning combination with Dr. Anurag Singh

Mitigating Muscle Loss from GLP-1 Agonists, with Dr. Anurag Singh

GLP-1 agonist drugs such as Wegovy and Ozempic have burst onto the scene, offering exciting prospects for metabolic health. And while I find the potential of these drugs truly fascinating, amidst their promising benefits, there’s a significant concern looming that can’t be overlooked —the risk of substantial muscle loss. It’s a topic that hits close to home for me, especially considering the pivotal role of muscle in overall health and longevity.

New Frontiers in Functional Medicine® Podcast

Tackling Alzheimer’s Disease Head On – the Inspiring Work of Dr. Heather Sandison

Today, I am honored to connect with Dr. Heather Sandison, whose work in reversing Alzheimer’s is nothing short of groundbreaking. Her dedication challenges the status quo of dementia care, offering real hope and tangible solutions. We’ll explore the intricacies of Alzheimer’s disease, from its elusive diagnosis to the shortcomings of traditional pharmaceuticals. Together, we’ll navigate the realm of evidence-based interventions, from early detection to personalized treatments, all aimed at optimizing cognitive function and overall well-being. Join us for a conversation that promises to ignite new possibilities in our approach to dementia care.

Reducing Senescent Cell Accumulation for Enhanced Longevity with Dr. Greg Kelly

Targeting Senescent Cells? Dose and Timing Matters – with Dr. Greg Kelly

I’m thrilled to welcome you to a truly fascinating discussion on the cutting edge of longevity medicine. In this episode, I sit down with the brilliant Dr. Greg Kelly to explore the complex world of cellular senescence and its profound implications for our aging process. We delve into the challenges of identifying these aging cells and the exciting research that’s paving the way for more accurate biomarkers. I’m particularly excited to share with you Dr. Kelly’s insights on how simple lifestyle changes, such as incorporating regular exercise and mindful caloric intake, can significantly reduce the accumulation of senescent cells. We also discuss some groundbreaking interventions, including the use of senolytic agents like quercetin, dasatinib, and piper longumine, and how they’re revolutionizing our approach to longevity.

Metabolic Engineering: The Science Behind Staying in the Zone with Dr. Barry Sears

Dr. Barry Sears (of Zone Diet Fame) on Lifetime Metabolic Health and Sourcing Omega-3s

In today’s episode, I’m thrilled to speak with Dr. Barry Sears, the creator of the Zone Diet, an approach that has not only topped bestseller lists multiple times but has also profoundly impacted nutritional practices really across the world. We dive into his transition from cancer research to nutritional science, focusing on how diet regulates the key areas of inflammation and hormonal balance. Dr. Sears shares insights from his groundbreaking work, exploring the balance of macronutrients and the pivotal role of omega-3 fatty acids and polyphenols. His contributions have revolutionized how we understand diet’s impact on health, offering valuable strategies for managing chronic diseases and optimizing wellness globally. You’ll find many clinical pearls in this conversation. Join us as I uncover the science and stories behind this influential dietary philosophy with this legend of nutrition and wellness. ~DrKF

Unraveling PCOS and Fertility: Debunking Common Misconceptions with Dr. Tara Harding

Unraveling PCOS and Fertility: Debunking Common Misconceptions with Dr. Tara Harding

Fellow clinicians, gear up for an enlightening dive with Dr. Tara Harding, a vanguard in the realm of women’s health and fertility. Renowned for her exceptional work as a family nurse practitioner and fertility coach, Dr. Harding brings a wealth of knowledge from her battle against infertility and medical gaslighting, all while breaking barriers and fostering a supportive community for those navigating the complex journey of infertility. This conversation not only highlights innovative diagnostic tools like Mira but also delves into the nuances of managing conditions like PCOS and endometriosis. Dr. Harding’s personal and professional journey is a beacon of hope and empowerment, underscoring the significance of comprehensive care in women’s health. Prepare to be inspired by her dedication to revolutionizing fertility care and advocating for patient empowerment.

AI, Digital Twins, and the Future of Personalized Medicine Interventions with Dr. Nathan Price

AI, Digital Twins, and the Future of Personalized Medicine Interventions with Dr. Nathan Price

I’m beyond thrilled to share this mind-blowing conversation with Dr. Nathan Price, Chief Scientific Officer of Thorne HealthTech and author of The Age of Scientific Wellness. Imagine harnessing AI to predict outcomes of our functional interventions (diet, supplements, lifestyle) by implementing a “digital twin” model that is populated with all of your patient’s bio data. Being able to test the response of our treatments (and importantly, the synergistic response of multimodal interventions! It’s heady stuff, but amazingly, it is where we are headed today. Dr. Price illuminates the incredible potential this technology brings for personalized evidence-based medicine in nutrition, tailoring interventions based on microbial markers, and addressing lifestyle changes for Alzheimer’s prevention. The podcast is a captivating exploration of cutting-edge concepts and provides a glimpse into the exciting future of healthcare. I was wowed by my convo with Nathan and can’t wait to start kicking the tires on this baby. I know you’ll feel the same.

Decoding Aging: The Science Of Cellular Rejuvenation With Dr. Vittorio Sebastiano

Decoding Aging: The Science Of Cellular Rejuvenation With Dr. Vittorio Sebastiano

It was a career-defining (and perhaps life changing) moment when Dr. Vittorio Sebastiano, a reproductive biologist by training, realized that because we are able to create life, that same body of information could be harnessed to create youth – that is, radically reverse our biological aging process to a younger time point without losing cellular identity. In 2014, he and his lab began unpacking this epiphany. They made the radical decision to conduct their investigations in human cells and tissue rather than in rodents, with the expectation that such a start would be a better bridge to human clinical trials. Flash forward a decade and Dr. Sebastiano and his team stand poised to begin trials in humans. Dr. Sebastiano is, in my opinion, one of the most extraordinary scientists in the longevity space today who flies under the radar of most of us in functional medicine.