Can We Regrow Joints and Reverse Inflammaging? New Research Suggests YES

What New Research Says About Cartilage Regeneration and Joint Longevity

Osteoarthritis affects millions—chronic pain, limited mobility, and a dramatically reduced quality of life. But what if the answer isn’t just about treating the joint, but the inflammation driving the damage? In today’s episode, Kiran Krishnan, a leading microbiologist and advisor to Calroy Health Sciences, unveils a groundbreaking approach to joint health. He explains how chronic low-grade inflammation fuels osteoarthritis and accelerates joint degeneration. Even more exciting? Cartigenix, a revolutionary product combining unique extracts from celery seed and Boswellia, is showing real potential to regenerate cartilage, reduce pain, and improve mobility. Kiran also dives into the fascinating link between osteoarthritis and cardiovascular disease, why supporting liver health plays a crucial role in optimizing joint repair and how preventative strategies like Cartigenix can protect your joints before they start to decline. This episode could change everything you know about managing inflammation and joint health—don’t miss it!

The Shocking Truth About Chronic Illness: How to Reset Your Nervous System & Slow Aging

The Truth About Chronic Illness: How to Reset Your Nervous System & Slow Aging

We’ve all had patients struggling with chronic conditions like long COVID, fibromyalgia, Lyme disease, and chronic fatigue. Despite all the tools in our functional medicine toolkit, there’s still something missing. How can we truly help them? I’m excited to have Ashok Gupta is back on the New Frontiers podcast to offer a new take on that healing from chronic illnessquestion. He explains that how many chronic diseases stem from a malfunction in the brain’s threat detection system, where the body overreacts to perceived threats, triggering immune, nervous system, or mood responses, . This creatinges a vicious cycle. Ashok shares how retraining the brain and calming the nervous system can reset the body’s response to chronic stress and presents the growing body of research supporting thehis Gupta Program, including new subjective measurements like CRP showing its impact. What excites me most is the potential for this approach to help some of my toughest-to-treat patients. With more studies emerging, I’m increasingly hopeful this could be a game-changer. It’s a conversation you won’t want to miss! ~DrKF

What Your Mitochondria Wish You Knew: A Look Inside Cutting-Edge Mitochondrial Science

Hidden Mitochondria Problems Are Accelerating Your Age & Draining Your Health

What if the key to reversing chronic disease, slowing cognitive decline, and boosting energy lies in the tiny powerhouses inside your cells—and we’ve finally found a way to protect them? We know mitochondria power our cells, but did you know they also create oxidative stress as they generate energy? Protecting mitochondrial health is critical—but most antioxidants can’t reach inside the mitochondria where protection is needed most—until now. MitoQ, a scientifically advanced, mitochondria-targeted antioxidant developed by visionary researchers in New Zealand penetrates mitochondria up to 90%, offering protection where it’s needed most. In this episode with Dr. Siobhan Mitchell, we dive into how MitoQ is transforming the way we tackle chronic disease, inflammation, and cognitive decline. From improving heart health to supporting brain function, MitoQ is changing the game. It’s something I’m using personally and recommending to most of my patients. Listen in to discover how this powerful tool can help you support your patients at the cellular level—before symptoms even appear. ~DrKF

Next-Gen Alzheimer’s Testing: The Power of p-Tau 217 and Blood-Based Biomarkers

p-Tau 217: The Breakthrough Biomarker Revolutionizing Early Alzheimer’s Detection

Join me for a fascinating conversation around an exciting breakthrough in dementia detection that’s offering real hope for early intervention. Dr. Hans Frykman, Chief Scientific Officer at Neurocode Laboratories, is here to share groundbreaking insights into cutting-edge biomarkers that can identify Alzheimer’s disease before symptoms even appear. What’s even more fascinating is how these same tools are revealing neuroinflammation caused by infections, including COVID, Lyme disease, and mold exposure—issues that are incredibly relevant in functional medicine today. The assays Dr. Frykman and his team have developed are transforming the way we think about diagnosing and addressing neurodegeneration. We’re talking about a potential game-changer that allows us to intervene earlier, reverse damage, and ultimately improve the trajectory of these conditions. This is an extraordinary time in science and medicine, and the work we’re discussing today is at the forefront of it all. Don’t miss out on how this could reshape your practice. ~DrKF

Cutting Edge Interventions For Patients with Adverse Food Reactions with Dr. Tom Fabian

Cutting-Edge Metabolomic Testing for IBS, Longevity, and Metabolic Health

We’re witnessing an exciting shift in how we understand gut health and disease—and it’s all thanks to the powerful metabolites produced by the microbiome, like short-chain fatty acids (SCFAs) and secondary bile acids. In today’s episode, Dr. Tom Fabian shares groundbreaking insights into how these postbiotics influence intestinal barrier integrity, immune balance, and even muscle regeneration. These compounds are also connected to key processes like glucose metabolism and healthy aging. What’s truly fascinating is how this science is opening up new frontiers in treating IBS, metabolic conditions, and chronic gut issues. With the upcoming launch of Diagnostic Solution Laboratories’ StoolOMX test an add-on to the GI-MAP, we now have a tool to measure these metabolites in clinical practice, making personalized and effective treatments more attainable. This is a pivotal moment in functional medicine that you don’t want to miss.

Exposomics and Precision Medicine: Redefining Chronic Disease with Environmental Insights

A Fresh Take on Exposomics: Resiliency Factors That Offset Environmental Risks

In this episode, we’re diving into exposomics—one of the most cutting-edge fields in environmental medicine. We in the functional medicine space have long embraced this approach that focuses on the lifelong effects of environmental exposures, from the prenatal period on, and how these exposures shape our health over time. I’m thrilled to have Drs. Robert and Rosalind Wright with us, pioneers in this field at Mount Sinai to share their research exploring how environmental factors, from lead and air pollution to social stress, can influence chronic diseases like asthma, obesity, Alzheimer’s, and autism.

Akkermansia: A Keystone Microbe for Longevity and Metabolism

This GLP-1-Supporting Probiotic Is A Constant In Our Longevity Stack

Join me and Dr. Colleen Cutcliffe, my brilliant friend, scientist, and the powerhouse CEO of Pendulum, for our deepest dive yet into all things Akkermansia. This free-flowing conversation will take your understanding of this extraordinary strain to a whole new level. We’ll explore Akkermansia’s pivotal role in metabolic health—think cravings, weight regulation, A1C—and why we’re deficient in the first place. Plus, we’ll discuss its connection to stress, anxiety, and even neurodegenerative diseases. We’ll also dive into the hotly debated topic of Akkermansia’s impact on MS, unpacking both sides of the controversy. And, we’ll touch on its promising influence on hormonal balance, from infertility to menopause. As someone who’s deeply invested in science, I’m personally bullish on Akkermansia and trust Pendulum’s products as part of my own foundational health stack. With groundbreaking science and fresh insights, this episode will change the way you approach your practice. ~DrKF

Healing Depression Project: Providing Hope For Treatment-Resistant Patients

Healing Depression Project: Providing Hope For Treatment-Resistant Patients

For many struggling with depression, the message they often hear from traditional care is “just live with it” or “there’s nothing more we can do.” In today’s episode, we’re challenging that narrative. I’m joined by Dr. Achina Stein and Silvia Covelli, the founders of the Healing Depression Project. Dr. Stein, a functional psychiatrist, and Silvia, who’s personally battled chronic depression, are offering a fresh approach to treatment-resistant depression. Their in-residence program, launching in March, takes a whole-person approach—integrating nutrition, lifestyle changes, trauma healing, and community support. And with research built into the program, they’re not just helping patients; they’re also paving the way to make this approach more accessible for everyone. If you’re ready to rethink depression treatment, this episode is for you. ~DrKF

NAD+ in the Spotlight: New Insights on Boosting Cellular Resilience

NAD+ in the Spotlight: New Insights on Boosting Cellular Resilience

I’m really excited about this one—Dr. Greg Kelly is back with us, and we’re diving deep into NAD, a molecule that’s finally getting the attention it deserves. If you’ve heard me talk about NAD before, you know how foundational it is for energy, longevity, and cellular health, but I’ve got to say—after today’s conversation, I’m looking at it in a whole new way. Dr. Kelly brings a fresh perspective on how NAD influences mitochondrial function, DNA repair, and even the aging process. He’s challenging the way we think about aging, and I’m here for it. For me, NAD is no longer just a side player—it’s going front and center in my supplement stack. If you’re wondering how it might show up clinically, whether it’s in fatigue or other signs of cellular stress, you’ll want to listen in. And if you’re like me, you’ll be adding this one to your regular routine. Have a listen and get ready to rethink how you approach aging and energy. ~DrKF

The Podcast After the Podcast: Revisiting Age Reversal with Dr. Greg Fahy

The Podcast After the Podcast: More on Age Reversal with Dr. Greg Fahy

I was thrilled to finally sit down with Dr. Greg Fahy, whose groundbreaking work in aging has truly reshaped our understanding of what’s possible. His 2019 TRIIM study, showing clear biological age reversal through thymus regeneration, was a game-changer. The scientific community was stunned, and rightly so—this was the first real evidence that we can turn back the clock on aging. But Dr. Fahy isn’t stopping there. His ongoing studies hold incredible implications for the future, from potentially reversing autoimmunity to avoiding transplant rejection. Even more exciting is the possibility of creating a standardized protocol that could help other clinicians use these principles in practice. We’re on the brink of something truly revolutionary, and I’m already looking forward to having him back to hear what’s next. This conversation is a must-listen for anyone passionate about the future of longevity. ~DrKF