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Strain-Specific Probiotics: Latest Evidence and Clinical Applications with Dr. Noelle Patno

What do we know about using specific probiotics for different health conditions? And is it time to move away from broad-spectrum probiotics and into condition-specific strains? With an explosion of new research on probiotics and a recent change in nomenclature, it’s easy to get confused. In this episode of New Frontiers, I lean on Dr. Noelle Patno’s extensive research knowledge to tease apart the science on probiotics. Dr. Patno holds a PhD in Molecular Metabolism and Nutrition and has designed and monitored clinical trials on microbiome and immune health. Together, we dive into the latest evidence on therapeutic uses of specific probiotic strains, including Lactobacillus rhamnosus GR-1, for women’s health and other conditions. Dr. Patno also shares excellent pearls on dosing, duration, delivery methods and antibiotic resistance. Many thanks to Noelle and the team at Metagenics for always leading the way and researching interventions.

Testosterone Therapy: Latest Evidence and Clinical Applications with Dr. Doreen Saltiel

Testosterone Therapy: Latest Evidence and Clinical Applications with Dr. Doreen Saltiel

Hormone therapy is still a highly controversial topic, fraught with lots of emotion, fear, and misleading information. And let me tell you: am I glad to be having a deep dive into the literature with my colleague and friend, the very brilliant Dr. Doreen Saltiel from Precision Analytical. She’s been practicing medicine for 40 years and preventative cardiology for more than 25 years. With advanced training in endocrinology as well as metabolic, anti-aging, and nutritional medicine, Dr. Saltiel is a leading expert on male and female hormone health. In this episode of New Frontiers, she brings her talent of dissecting the scientific evidence on testosterone deficiency and shares excellent clinical pearls to guide both physicians and patients in making decisions around hormone therapy. Folks, you’ll want to bookmark this one and save the show notes. Thanks for reading, sharing, and commenting!

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How to Fix the Vascular Health Crisis: The Endothelial Glycocalyx

We are living in times of great medical discoveries and advancements and today I am thrilled to talk about a relatively unknown structure: the endothelial glycocalyx (EGX). EGX can profoundly affect overall health – after all, you can’t have healthy organs and tissues if blood vessels are not healthy. Today on New Frontiers, I am joined by Dr. Kristine Burke a board-certified family, sports and functional medicine physician, and medical director for Help Your Diabetes Sacramento, where we discuss the full breadth of EGX functions and why it’s critical for cardiovascular health and so much more. Dr. Burke shares her exciting clinical experience and impressive findings from her case study series using Arterosil for plaque regression in some of her toughest patients. It’s a fascinating and enlightening conversation, so tune in and get ready to take some notes! Thanks for listening, and your support of New Frontiers.

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Latest Insights into the Role of the Gut Microbiome in Healthy Aging

Folks, I’m thrilled to be back once again with my friend and colleague, Dr. Tom Fabian, functional nutrition practitioner whose training originates in molecular biology of aging. Together with his training and experience as the clinical laboratory consultant for Diagnostic Solutions Lab, Dr. Fabian shares a wealth of practical applications for microbiome research in functional medicine and clinical settings. We also explore key microbial species for longevity and how to boost their levels, inflammaging of the microbiota, often-missed leaky gut clues on GI-MAP reports, the small intestine as a key site for immune tolerance, how microbiota influence epigenetics and much more. It’s truly exciting to learn from his extensive research expertise in the role of human microbiome and health, chronic disease and aging, so make sure you get ready to take notes and bookmark this page – you’ll want to come back for more! Thanks for listening, and leave us a review wherever you listen to New Frontiers! ~DrKF

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Immuno-Senescence: What Clinicians Need to Know with Dr. Joseph Raffaele

Folks, if you’ve been following me for any time, you I am fascinated with reversing epigenetic aging. With such research rapidly evolving, there’s always something new to talk about and my guest today has become a friend and a regular on the New Frontiers podcast – Dr. Joseph Raffaele: renowned expert on telomere biology and age management medicine. Dr. Raffaele, who is board-certified in internal medicine, diplomat at the American Board of Anti-Aging Medicine AND co-founder of PhysioAge Systems, joins me for the third time to talk about the latest in immunosenescence and aging. (You can find links to our previous conversations and related content in the shownotes.)

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Using Metabolomic Analysis For Clinical Insight

So many of us in functional medicine use urine organic acids as an assessment tool, yet we rarely pause to think how they are so intricately connected with the wider world of applied metabolomics. And we should because research shows that a broader view of metabolomics (i.e. not just your standard organic acid markers) results in a six-fold higher diagnosis rate compared to traditional assessment methods. Impressive, isn’t it? I’m thrilled to be joined by my dear friend and metabolomics expert Dr. Betsy Redmond in today’s podcast.

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What does “Evidence-based” look like in Functional Lab Testing?

As the name suggests, New Frontiers is about staying ahead of the curve in functional medicine, continually asking critical questions, and being open to self-critique. This couldn’t be more true than when it comes to advanced functional testing. Today I’m pleased to talk with a familiar face and renowned hormone testing expert, my friend Mark Newman. Mark created the DUTCH test based on his decade-long experience in novel test development, and joins New Frontiers to talk about all things hormones: from cortisol & thyroid health to estrogen, progesterone and androgens, the importance of analytical and clinical validation of tests, and his upcoming research on various hormone replacement therapy methods.

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Exploring Longevity Medicine and Epigenetic Aging with Dr. Lucia Aronica

What can queen bees teach us about epigenetics? And what do polyphenols, stress, and sunlight have in common? Hint: it has to do with longevity science. To mark our exciting paper on the Potential Reversal of Epigenetic Age Using a Diet and Lifestyle Intervention we are hosting a series of podcasts focused on the science of epigenetics and longevity, and kick things off with talented researcher and Stanford lecturer, Dr. Lucia Aronica. Dr. Aronica is a passionate advocate of lifestyle medicine and is currently leading the epigenetic analysis for the largest randomized clinical trial in the field of personalized nutrition on low carb vs. low fat diets.

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Comparing Saliva, Urine, and Serum Hormone Testing: Choosing the Best Test for Each Patient

Have you ever looked at serum hormone levels and scratched your head, wondering why there was such a difference between your patient’s clinical signs and the numbers on the report? Felt unsure whether to look at bioavailable hormone markers or their metabolites? Not surprisingly, when it comes to endocrinological health, there are just as many questions as hormones (and there are over 50!). My guest in this podcast, Dr. Lylen Ferris, gives us very clear and user-friendly guidance on appropriate hormone testing, interpreting results from different specimens and, most excitingly, using novel biomarkers, such as allopregnanolone. Having completed her naturopathic residency with Dr. Kimberly Windstar, and after years of teaching and mentoring medical students on gynecology and women’s health, Dr. Ferris has plenty of brilliant clinical pearls to share with us! Please share, comment, and leave us a starred review if you wouldn’t mind! Thank you!

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The Cell Danger Response: Restoring Cellular Health with Phospholipids and Bioactive Lipids

I am always eager to learn from other clinicians about how they approach complex patients and layer various healing modalities into the therapeutic encounter. My guest today, Dr. Bruce Hoffman MD, has combined his passion in integrative medicine with psychiatry to explore cellular health to best guide his patient’s health journey. Dr. Hoffman is based in Calgary, Canada at the Hoffman Centre for Integrative Medicine and the Brain Center of Alberta. He’s an IFM-certified functional medicine practitioner, board-certified in anti-aging and regenerative medicine (Shoemaker’s mold protocol), a certified Ayurvedic practitioner (Bredesen’s ReCODE treatment), certified as a family constellation therapy specialist, (ILADS for Lyme and co-infections), and trained in Chinese medicine, to name just a few of his substantial specialties. He knows his stuff. Tune in for this thought-provoking conversation as we explore the role the psyche plays in disease and healing, including clinical pearls, interventions, and effective supplementation. Listen, share, and leave a starred rating, if you wouldn’t mind! Thanks for listening.