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Using Metabolomic Analysis For Clinical Insight

So many of us in functional medicine use urine organic acids as an assessment tool, yet we rarely pause to think how they are so intricately connected with the wider world of applied metabolomics. And we should because research shows that a broader view of metabolomics (i.e. not just your standard organic acid markers) results in a six-fold higher diagnosis rate compared to traditional assessment methods. Impressive, isn’t it? I’m thrilled to be joined by my dear friend and metabolomics expert Dr. Betsy Redmond in today’s podcast.

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What does “Evidence-based” look like in Functional Lab Testing?

As the name suggests, New Frontiers is about staying ahead of the curve in functional medicine, continually asking critical questions, and being open to self-critique. This couldn’t be more true than when it comes to advanced functional testing. Today I’m pleased to talk with a familiar face and renowned hormone testing expert, my friend Mark Newman. Mark created the DUTCH test based on his decade-long experience in novel test development, and joins New Frontiers to talk about all things hormones: from cortisol & thyroid health to estrogen, progesterone and androgens, the importance of analytical and clinical validation of tests, and his upcoming research on various hormone replacement therapy methods.

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Exploring Longevity Medicine and Epigenetic Aging with Dr. Lucia Aronica

What can queen bees teach us about epigenetics? And what do polyphenols, stress, and sunlight have in common? Hint: it has to do with longevity science. To mark our exciting paper on the Potential Reversal of Epigenetic Age Using a Diet and Lifestyle Intervention we are hosting a series of podcasts focused on the science of epigenetics and longevity, and kick things off with talented researcher and Stanford lecturer, Dr. Lucia Aronica. Dr. Aronica is a passionate advocate of lifestyle medicine and is currently leading the epigenetic analysis for the largest randomized clinical trial in the field of personalized nutrition on low carb vs. low fat diets.

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The Impact of Therapeutic Dietary Interventions on Disordered Eating

For clinicians, therapeutic dietary interventions such as an elimination diet, a cardiometabolic diet, intermittent fasting, or caloric reduction, are some of the most important tools we have in functional medicine. Transitioning to healthful eating can for some patients be a joyous experience of liberation, but then for others it can be restrictive and problematic, and sometimes fall in the continuum of eating disorders. How do we tease this out? How do we screen for vulnerability in disordered eating and support patients who fall within this spectrum? In this episode of New Frontiers, Dr. Carolyn Fisher PhD, a licensed clinical psychologist who specializes in helping individuals with binge eating, emotional eating, chronic dieting, and other medical conditions heal their relationships with food.

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The Role of Neuroplasticity in Chronic Illness & Healing

Within the realm of functional medicine, we are quite successful at restoring some order to this cacophonous symphony of chronic illness, and getting our patients better to an extent. However, there is a final piece – a missing piece, if you will – and my guest today, Ashok Gupta, shares how neuroplasticity affected his own healing journey of chronic fatigue syndrome and why this final piece is integral to restoring optimal health. Ashok is a speaker, filmmaker, and health practitioner who created a program for retraining the brain using interventions to facilitate neuroplasticity. In this episode of New Frontiers, we discuss neuroplasticity dysfunction, how to rewire the brain’s survival response, and so much more. Folks, this conversation goes well beyond the patient-physician encounter and explores the depths of our homes, our communities, and how we experience the world around us. Stay tuned, leave us a comment, and subscribe to stay up to date on our latest content! ~DrKF

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Comparing Saliva, Urine, and Serum Hormone Testing: Choosing the Best Test for Each Patient

Have you ever looked at serum hormone levels and scratched your head, wondering why there was such a difference between your patient’s clinical signs and the numbers on the report? Felt unsure whether to look at bioavailable hormone markers or their metabolites? Not surprisingly, when it comes to endocrinological health, there are just as many questions as hormones (and there are over 50!). My guest in this podcast, Dr. Lylen Ferris, gives us very clear and user-friendly guidance on appropriate hormone testing, interpreting results from different specimens and, most excitingly, using novel biomarkers, such as allopregnanolone. Having completed her naturopathic residency with Dr. Kimberly Windstar, and after years of teaching and mentoring medical students on gynecology and women’s health, Dr. Ferris has plenty of brilliant clinical pearls to share with us! Please share, comment, and leave us a starred review if you wouldn’t mind! Thank you!

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Nutrition’s Role in the Epigenetic Origins of Health and Disease with Judith Finlayson

Since the time of mapping out the genome in 2000, we’ve continued to connect the dots between generational experiences, particularly trauma and in utero exposures, and the development of health and disease. We’ve seen, for instance, from survivors of the Dutch Hunger Winter or the Holocaust, epigenetic changes that are passed on to future generations. My guest in this podcast, best-selling author and former journalist Judith Finlayson, discusses the fascinating history the led to our current understanding of epigenetic expression. She shares research from her book, You Are What Your Grandparents Ate: What You Need to Know About Nutrition, Experience, Epigenetics and the Origins of Chronic Disease, and dives into the dietary and lifestyle choices she prioritizes to support optimal genetic expression. Listen, learn, and leave a review/rating wherever you’re listening to New Frontiers!

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The Cell Danger Response: Restoring Cellular Health with Phospholipids and Bioactive Lipids

I am always eager to learn from other clinicians about how they approach complex patients and layer various healing modalities into the therapeutic encounter. My guest today, Dr. Bruce Hoffman MD, has combined his passion in integrative medicine with psychiatry to explore cellular health to best guide his patient’s health journey. Dr. Hoffman is based in Calgary, Canada at the Hoffman Centre for Integrative Medicine and the Brain Center of Alberta. He’s an IFM-certified functional medicine practitioner, board-certified in anti-aging and regenerative medicine (Shoemaker’s mold protocol), a certified Ayurvedic practitioner (Bredesen’s ReCODE treatment), certified as a family constellation therapy specialist, (ILADS for Lyme and co-infections), and trained in Chinese medicine, to name just a few of his substantial specialties. He knows his stuff. Tune in for this thought-provoking conversation as we explore the role the psyche plays in disease and healing, including clinical pearls, interventions, and effective supplementation. Listen, share, and leave a starred rating, if you wouldn’t mind! Thanks for listening.

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Integrative Protocols: Focus on Senolytics, Cell Senescence, and the Role of Telomerase Activation

Colleagues, if you’ve been following me for any time, you’ve heard me speak frequently about aging as the top driver of chronic disease. In today’s interview, I dive into evidence-based integrative protocols to prevent and reverse the aging process. My guest, Dr. Joseph Cleaver MD, is a Fellow of the American Board of Anti-aging and Regenerative Medicine, is board-certified in internal medicine, a rheumatologist, on faculty at A4M and MMI and has authored and published a wealth of research and scholarly articles. He founded Paradigm Wellness Medical Group in Dallas and Sonoma Valley, California, AND he is Medical Director at Boutique Wellness in Winston, North Carolina. Folks, you’ll want to be ready to take notes during this interview, as Dr. Cleaver shares his personalized senolytic protocols specific to patient phenotypes. Listen, share, and leave a starred rating, if you wouldn’t mind! Thanks for listening. ~DrKF

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Functional Medicine’s Role in the Pandemic Era with Amy Mack and Dr. Patrick Hanaway

This is an exciting year for us in functional medicine, with the Institute of Functional Medicine (IFM) celebrating its 30-year anniversary alongside its Annual International Conference (AIC) on resilience in functional medicine. My guests in this podcast, Dr. Patrick Hanaway MD and Amy Mack CEO of IFM, join me to discuss how functional medicine is addressing the triple pandemic of COVID-19, racism, and economic crisis. Dr. Hanaway is a board-certified family physician, senior advisor to Amy Mack at IFM, and a founding medical director at the Cleveland Clinic Center for Functional Medicine. Amy Mack spent the last three decades in mission and service-oriented organizations and is now helping lead the IFM through uncomfortable territory as they not only offer evidence-based education but take action on the most pressing issues we are currently facing within our communities and healthcare. This is a powerful conversation with an important call to action, so stay tuned to learn more about the COVID-19 tools IFM has created for practitioners and patients as well as highlights on IFM’s upcoming AIC. Settle in, this is a good one and sneak peak at the exciting schedule for AIC! As always, thanks for listening, and I so appreciate any comments, reviews, and ratings wherever you listen to New Frontiers.