Intriguing new research shows that it is possible to reverse age-related cellular dysfunction in vivo, specifically age-related vision loss. This suggests that modifying epigenetic expression is a powerful tool to counteract the damage of aging. The study published in Nature sought to reset the epigenome and DNA methylation patterns by expressing transcription factors, which help…
A sedentary lifestyle is associated not only with a higher risk of early death and also an increased risk of chronic diseases such as heart disease and type 2 diabetes. If you’re like one of the millions of people in a sedentary job or lifestyle, you may wonder how to counteract the negative health impacts…
More research confirms that maintaining optimal vitamin D levels is extremely important for reducing the risk of infection with SARS Cov-2. A six-week observational study of 154 people published in Nature found that 97 percent of individuals with severe COVID-19 had vitamin D deficiency (mean concentration was 14 ng/mL) compared to 33 percent of people…
The results from a newly-published trial on the effects of a dietary intervention in overweight adults are impressive: 14 lbs weight loss, increased insulin sensitivity, a 19.3 mg/dL reduction in total cholesterol, 15.4 mg/dL reduction in LDL cholesterol, and reduced fat distribution in the liver and muscles (associated with reduced risk for fatty liver and…
A large number of cancer therapies are approved by the FDA without randomized clinical trials and only increase median survival by 2.4 months, according to a new review article published in the Journal of the American Medical Association (JAMA). This may come as a surprise and disappointment considering the urgent goals of cancer research to…
People of all ages, from kids to older adults, are encouraged to limit sedentary behavior and increase daily exercise, according to updated guidelines from the World Health Organization (WHO). These guidelines, which replace 2010 WHO recommendations, highlight the importance of combining aerobic plus strength training, and include guidance for pregnancy, postpartum women, and individuals with…
Some of our favorite polyphenol-rich foods, including green tea, muscadine grapes, cacao, and dark chocolate appear to block an enzyme in the SARS-CoV-2 virus, inhibiting its replication. A docking simulation and in vitro study published in Frontiers in Plant Science found that these flavan-3-ol and proanthocyandin-containing foods can block and bind the function of this enzyme, or protease, which…
Supplementing with melatonin may decrease the likelihood of contracting COVID, particularly among African Americans. Researchers analyzed data from an observational study of over 26,000 people from a COVID-19 registry at the Cleveland Clinic Health System and found that melatonin use is associated with a 52% reduced likelihood of a positive SARS-CoV-2 test in African Americans.…
People who have been exposed to a seasonal “common cold” may experience less severe COVID-19 symptoms. While we’ve discussed this topic previously, a study from the Journal of Clinical Investigation reports the first clinical evidence of cross reactivity with the common cold and COVID. This is due to previous immune responses against the four endemic…
Scientists are continuing to explore the role of furin proteases in the development of drugs to address COVID infections. This is a topic Dr. Fitzgerald has written on previously, including a peer-reviewed publication discussing dietary, lifestyle, and natural options to consider for lowering furin levels.
