Despite a dramatic rise in antidepressant use in the United States since 1988, the number of Americans suffering from depression has not decreased. This leaves clinicians with a stark reality: more medication, without improvement. This reality raises the central question that inspired the Healing Depression Project: Is depression truly treatment-resistant, or are current treatments simply not effective?
DetailsIn this practitioner spotlight, Dr. Darisa Espinal, naturopathic physician at Dr. Kara Fitzgerald’s New Frontiers Functional Medicine Clinic, shares her journey into functional medicine, the types of patients she supports, and how she integrates longevity medicine and root-cause care to help patients achieve optimal health and vitality. Dr. Espinal, can you share your path to becoming a functional medicine doctor and how your training shaped your approach to patient care?
DetailsOsteoarthritis (OA) is a debilitating, chronic joint disease affecting about 33 million adults in the United States. As the aging population grows and obesity rates climb, this number is expected to surge. By 2030, nearly 67 million Americans will be living with arthritis, with OA being the most prevalent form. OA is not just a condition of the joints – it’s a systemic burden that increases the risk of serious comorbidities such as cardiovascular disease, type 2 diabetes, and depression, significantly impairing quality of life and increasing healthcare costs.
DetailsLet’s be honest, the term “longevity medicine” has gotten a bit of a reputation lately. For many of us in functional medicine, it can feel like the exclusive domain of elite biohackers or billionaires chasing the next shiny object. I hear it from practitioners all the time: “Longevity isn’t for me. It’s all hype, no science.” Or “It feels disconnected from the work I do every day with real patients.” But I’m here to tell you that couldn’t be further from the truth. In fact, I would argue that Functional Medicine Is Longevity Medicine. Always has been. This is exactly why I created the Functional Medicine IS Longevity Medicine Masterclass: For Clinicians, happening live, virtually, and for free, September 17–19, 2025. Because it’s time we reframe the narrative and take our seat at the table. Or better yet, remind folks that we built the table.
DetailsWith thanks to Romilly Hodges, CNS, for her contributions to this article. I’m not here to fan the flames of controversy, but I do believe in asking smart, systems-oriented questions—especially when we’re talking about chemicals that may be added to something as essential as drinking water. Fluoride is one of those topics that sits right…
DetailsWe are delighted to announce that Dr. Kirsten FitzGerald*, DNP, FNP-BC, has joined the clinical team at the New Frontiers Functional Medicine Clinic. With a strong background in functional and integrative medicine, Dr. Kirsten brings a thoughtful, science-backed approach to healing that perfectly aligns with our clinic’s mission: to provide personalized, root-cause care that empowers patients to take charge of their health.
DetailsUrolithin A is rapidly becoming a go-to longevity nutrient, and with good reason. Backed by 15 years of research and 11 human clinical trials, it is one of the most extensively studied compounds for healthy aging.
DetailsWhen I was a kid at lunch, while my friends were eating those heavenly-looking ultraprocessed Twinkies and Ringdings and making dough balls with their white bread, I ate home-made yogurt or nutbutter sandwiches on a very dense, whole grain bread; or perhaps noshed on some sardines. Make no mistake, I went through a very rebellious phase involving Oreo cookies when I finally called the food shots in my life. But thankfully, I had gleaned enough from my mom that this phase didn’t last long. Indeed, I developed a deep appreciation for how savvy she was (and still is!) when it comes to keeping food clean, healthy and almost completely free of ultraprocessing and toxic food chemicals. She taught me the importance of avoiding ultra-processed foods and toxic food chemicals, long before it became a public health headline.
DetailsEstrogen is a life-giving hormone with which modern humans have a complicated relationship. Over two decades ago, The Women’s Health Initiative (WHI) findings mistakenly reported that combined estrogen and progestin hormone therapy increased the risk of breast cancer, coronary heart disease, stroke, and venous thromboembolism in postmenopausal women. This led to a pervasive vilification of estrogen therapy that has affected generations of women.
DetailsDiscover the truth about olive oil. Dr. Artemis Morris busts common myths and shares science-backed benefits of this Mediterranean staple.
DetailsSleepless nights can be more than just an occasional inconvenience—they often come with exhaustion, frustration, and confusion about why nothing seems to help. If you’ve (or your patients have) tried different remedies but still struggle to get quality rest, understanding the specific nature of insomnia is the key to unlocking deeper, restorative sleep.
DetailsProtecting your skin from UV radiation isn’t just about minimizing sunburns—it’s about slowing a significant accelerant of biological aging that triggers oxidative stress, immune suppression, and cellular senescence. While traditional sunscreens are a barrier to limiting UV exposure, they aren’t perfect alone. They can wash or rub off easily, degrade when exposed to heat and sunlight, and don’t address the downstream photodamage that continues long after exposure. That’s where antioxidants come in—they target oxidative stress, support cellular repair, and fortify your skin’s intrinsic UV defenses. Let’s explore the mechanisms of antioxidant-driven photoprotection and how integrating these compounds into your regimen can enhance skin longevity and resilience.
DetailsStarting and growing an integrative medical practice is a transformative journey that requires careful planning, commitment, and adaptability. Often, integrative and functional medicine providers are great clinicians when it comes to helping their patients, but feel inadequately prepared to run the business side of their practice. Dr. Linda Matteoli, at Origins Incubator, has the solution to this conundrum, walking physicians through the process to increase confidence, maintain authenticity, and achieve outcomes. The strategies they share in this article are valuable for all of us. – DrKF
DetailsBy the end of my book tour in 2022—one of the most amazing but intense experiences of my life—you could scrape me off the floor. (Who knew? I certainly didn’t expect it.) I was wiped out. My Oura data corroborated what I was feeling, and, particularly devastating, my HRV was stuck in the low teens. Thank goodness I’d layered an extremely needed vacation into the book experience, and we headed off to Baja California Sur. It was this vacation—and my almost immediate HRV rebound—that prompted me to trade the high-stress East Coast lifestyle for a more balanced, nurturing environment in Mexico longer term.
DetailsMitochondria are crucial for life, and increasingly research is finding that they hold the key to better aging and longevity, as a critical hallmark of aging. While optimising mitochondrial health through exercise, diet, and stress management is essential for maintaining their function, targeted, research-backed mitochondrial solutions are proving effective at unlocking a new level of longevity-focused results.
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I am eternally grateful to our sponsors who, by advertising with us, enable me and my team to devote energy and time to writing and publication. All the companies who sponsor us are companies that I trust for myself and my patients and use regularly in my clinical practice. Please check out their websites! – Dr. KF
Dr. Fitzgerald is an internationally-recognized expert clinician, as well as nationally-bestselling author, who is actively engaged in clinical research on epigenetics and longevity using a diet and lifestyle intervention developed in her research and practice.
She has published two clinical studies on the potential bioage-reversing effects of an 8-week DNA methylation-supportive diet and lifestyle in middle-aged men and women in the journal Aging. She continues to lead the conversation around interventions for healthy aging and their extensive potential in improving individual and population level disease burdens, while also providing evidence-based and practical advice that cuts through the hype.
Dr. Fitzgerald is on faculty at the Institute for Functional Medicine (IFM), is an IFM Certified Practitioner, and lectures globally on functional medicine, longevity, and epigenetics to practitioners and consumers.
She maintains an award-nominated podcast series ranked in the top 1% of global podcasts by Listen Score, New Frontiers in Functional Medicine, and an active blog and Clinic Immersion webinar series through her website, www.drkarafitzgerald.com.
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