From Hot Flashes to Healthspan: The FxMed Guide to Hormones & Longevity

From Hot Flashes to Healthspan: The FxMed Guide to Hormones & Longevity

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Few guests bring the kind of insight and energy that Dr. Carrie Jones does. She’s a dear friend, a brilliant colleague, and truly deserves her title of Queen of Hormones. With more than twenty years in women’s health and endocrinology, she has helped shape how we think about hormone testing and education in functional medicine. In this conversation, we dive into women’s hormones across the lifespan, with an extra focus on perimenopause, and how it ties back to mitochondrial health. Carrie brings humor and clarity to even the most complex topics, dropping clinical pearls along the way. It’s a fascinating and genuinely hopeful discussion you won’t want to miss. ~DrKF

Targeting Immune Aging: New Findings from the MitoImmune Study on Urolithin A (Mitopure®)

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Can Mitopure®, and its active ingredient Urolithin A, support an aging immune system? As we recognize immune aging as a primary driver of age-related disease, this question has taken on new clinical importance. The newly published MitoImmune study in Nature Aging provides the first rigorous clinical evidence to address this question. Conducted by researchers from Timeline, the Buck Institute for Research on Aging, and the lab of Professor.

Guide to Building a Sustainable Concierge Longevity Practice

Guide to Building a Sustainable Concierge Longevity Practice

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It really takes courage to completely change course and walk away from a successful hospital medicine career. Dr. Brooke Stubbs did just that after realizing the pace and pressure of her work were costing her health. She found her way to lifestyle medicine, and that shift changed everything about how she practices—and how she lives. In our conversation, Brooke talks about what she’s learned along the way—how to build a concierge practice that actually works, set boundaries, create supportive systems, and price her services in a way that’s fair and sustainable. She also shares how Vibrant’s customizable panels have helped her provide consistent, comprehensive care. I love her honesty about learning through trial and error and her passion for building community. Her story is such a great reminder of what’s possible when we combine science, purpose, and heart in medicine. ~DrKF

Reversing Aging: Screening, Wearables & What To Do Now

Reversing Aging: Screening, Wearables & What To Do Now

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When I sit down with Sergey Young, I’m always struck by the balance he brings. He’s deeply embedded in the future of longevity science, yet he champions the fundamentals we already know work: nutrition, exercise, sleep, purpose, and medical screening. For me, that’s a powerful reminder that as functional medicine practitioners, we already have the tools to help patients live longer, healthier lives. What excites me in this conversation is how Sergey shows us that the technologies on the horizon, including AI drug discovery, blood-based cancer tests, organ regeneration, and wearables, are making these solutions more affordable, more immediate, and more engaging for our patients. This isn’t just a distant dream. It’s a glimpse of where medicine is heading, and we are well positioned to lead the way. ~DrKF

Aging & Hair Loss Explained: OS-01’s Science-Backed Approach

Aging & Hair Loss Explained: OS-01’s Science-Backed Approach

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Hair loss isn’t just cosmetic. It’s a visible marker of aging biology and a profound emotional burden, and I think this is even more true for women. The last time Carolina Reis Oliveira joined me on the podcast, we explored the OS-01 peptide for skin. This time, she’s back to share new research on how it can be applied to hair, not only outperforming minoxidil in clinical trials but also pointing us toward protocols that address stress, hormones, UV exposure, and the scalp microbiome. I love OneSkin’s deep commitment to science and the curiosity that drives their work, which is exactly what allows them to bring discoveries like this forward. This is the kind of science that changes the way we think about both aging and patient care. ~DrKF

Why Functional Medicine Is the Future of Longevity

Why Functional Medicine Is the Future of Longevity

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This is the longevity conversation functional medicine providers need to hear. What struck me in each of these conversations is how deeply functional medicine already holds the answers we’re chasing in longevity science. We don’t need to reach for extremes. The tools we use every day—our frameworks, our lens, our root-cause approach—are longevity medicine. If you’re a clinician who’s felt unsure about where you fit in this rapidly growing space, I want this episode to remind you: you’re already in it. You’ll hear how leaders in our field are using the functional medicine matrix to slow cognitive decline, decode inflammatory pathways, and reframe aging itself as a process we can impact—intelligently and safely.

Why Centenarians Are Defying Science: Secrets to Living 100+

Why Centenarians Are Defying Science: Secrets to Living 100+

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This conversation with Dr. Nir Barzilai is one of the most thought-provoking we’ve had on New Frontiers. His decades of research on centenarians, biological age, and the hallmarks of aging have shaped how we think about longevity—and what’s possible when we start targeting aging itself, not just individual diseases. We get into the science behind why some people live 20–30 years longer and healthier, and what it means to measure the biological age of individual organs. But we also hit a few sparks—especially when it comes to nutraceuticals and the role of metformin in prevention. I don’t agree with everything you’ll hear, and I followed up with Dr. Barzilai afterward to unpack some of the more provocative claims. We may just need a second round for this one… stay tuned.

The Science-Backed Bitter Compound That Mimics GLP-1 (No Injections Needed!)

The Science-Backed Bitter Compound That Mimics GLP-1 (No Injections Needed!)

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I’ve been watching the science behind Calocurb evolve over the last year, and I have to say—this is one of the most exciting clinical tools I’ve seen emerge in the metabolic space in quite some time. A hops-derived compound that stimulates endogenous GLP-1, CCK, and PYY—without a prescription or injection? That’s a big deal, especially for patients struggling with appetite regulation, weight plateaus, or the aftermath of GLP-1 discontinuation.